| 引用本文:张金彦.中西医药物方案对血管神经性头痛患者的治疗效果及其药学安全性分析[J].世界中医药,2018,(01):. |
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| 中西医药物方案对血管神经性头痛患者的治疗效果及其药学安全性分析 |
| Therapeutic Effects of Method of Chinese and Western Medicine in the Treatment of Patients with Vascular Neurogenic Headache and Analysis of its Pharmaceutical Safety |
| 投稿时间：2017-12-01 |
| DOI：10.3969/j.issn.1673-7202.2018.01.022 |
| 中文关键词: 血管神经性头痛 西药 强力定眩片 安全性 |
| English Keywords:Vascular neurogenic headache Western medicine Qiangli Dingxuan Pills Safety |
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| 中文摘要: |
| 目的：考察中西医结合治疗血管神经性头痛的临床效果及用药安全性。方法：选取2016年1月至2017年6月北京市第二医院门诊收治的血管神经性头痛确诊患者156例进行随机对照临床研究。按照随机数字表法将患者分为2组，一组经常规西药治疗（常规西药组，78例），另一组经西药联合中药治疗（中西药联用组，78例）。常规西药治疗包括：口服盐酸氟桂利嗪胶囊（5 mg/次，1次/d）。中药治疗：口服强力定眩片（0.35 g/片，1.4 g/次）。比较2组治疗后头痛的改善，临床效果，生命质量，用药安全性。结果：2组患者的头痛症状、生命质量均较其治疗前有明显的改善。与常规西药组比较，中西药联用组患者头痛的改善更佳（t＝4.23,P<0.05），获得的临床效果更好(Uc=4.99，P<0.05)，该组患者在生命质量的躯体生理(PF)、心理/情绪（RE）、社会功能(SF)及总体健康(HT)这几个维度的改善更为显著（P均<0.05），但其药物不良反应的发生率并未增加(P>0.05)。结论：治疗血管神经性头痛推荐采用常规西药和联合中药的联合用药方案，可良好改善患者的头痛症状，提高其生命质量，且用药安全性良好。 |
| English Summary: |
| To investigate therapeutic effects of the method of Chinese and western medicine in the treatment of patients with vascular neurogenic headache and analysis of its pharmaceutical safety. Methods: A total of 156 cases of patients with vascular neurogenic headache were admitted and treated in the clinic of the Second Hospital of Beijing from June 2016 to January 2017. According to the random number table method, all the patients were divided into two groups: conventional western medicine group (conventional western medicine treatment, 78 cases) and combination of Chinese and western medicine group (western medicine combined with Chinese medicine treatment, 78 cases). The conventional western medicine treatment included: oral administration of Flunarizine Hydrochloride Capsules (5 mg/time, 1 time/day). Chinese medicine treatment included: oral adminiarestion of Qiangli Dingxuan Pills (1.4 g/time, 3 times/day). The improvements of headache, the clinical effect, the quality of life and the safety of medication were compared in the two groups after treatment. Results: The symptoms of headache and the quality of life in the two groups were all improved than that before treatment. After treatment, compared with conventional western medicine group, , headache was improved better (t=4.23, P<0.05) in the combination of Chinese and western medicine group, and with better clinical effects (Uc= 4.99, P<0.05). The quality of life including body physiological (PF) , psychological / emotional (RE), social function (SF) and general health (HT) were all improve compared with the conventional western medicine group (P<0.05), while the drug adverse reactions did not increase (P>0.05). Conclusion: The combination of conventional western medicine and traditional Chinese medicine is recommended for the treatment of vascular headache. It can improve headache symptoms and quality of life, and is safe in medication. |
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