| 引用本文:叶素明，周凯.血塞通软胶囊联合超声乳化术治疗非增殖性糖尿病视网膜病变合并白内障的临床观察[J].世界中医药,2018,(01):. |
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| 血塞通软胶囊联合超声乳化术治疗非增殖性糖尿病视网膜病变合并白内障的临床观察 |
| Clinical Observation on Xuesaitong Soft Capsule Combined with Phacoemulsification in Treating Non-proliferative Diabetic Retinopathy (NPDR) and Cataract |
| 投稿时间：2017-12-20 |
| DOI：10.3969/j.issn.1673-7202.2018.01.024 |
| 中文关键词: 血塞通软胶囊 非增殖性糖尿病视网膜病 白内障 超声乳化术 |
| English Keywords:Xuesaitong soft capsule Non-proliferative diabetic retinopathy Cataract Phacoemulsification |
| 基金项目:云南省重大科技专项（2015ZJ009）——心脑血管药物开发专题--络泰·血塞通软胶囊大品种培育及二次开发 |
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| 中文摘要: |
| 目的：观察血塞通软胶囊联合超生乳化术治疗非增殖性糖尿病视网膜病变合并白内障的疗效与安全性。方法：选取2015年1月至2015年6月成都市温江区人民医院收非增殖性糖尿病视网膜病变合并白内障患者治的108例（116眼），随机分为2组，对照组54例（白内障57眼），观察组54例（白内障59眼）。所有患者均给予常规降糖治疗及超声乳化术，其中观察组患者术前2周至术后3个月给予血塞通软胶囊。观察糖尿病视网膜病变疗效、视力和视野平均缺损、角膜散光度和超声乳化术并发症。结果：观察组总有效率高于对照组（P<0.05）；术后1周、术后3个月2组患者的视力和视野平均缺损均得到持续改善（P<0.05），且观察组优于对照组（P<0.05）；术后1周2组患者的角膜散光度均显著上升（P<0.05），术后3个月恢复至术前（P>0.05），且组间无统计学意义（P>0.05）；观察组超声乳化术并发症率低于对照组（P<0.05）；未观察到药物相关不良反应。结论：血塞通软胶囊联合超声乳化治疗非增殖性糖尿病视网膜病变合并白内障疗效好，能改善患者视力、平均视野缺损，降低超声乳化术并发症。 |
| English Summary: |
| To observe the efficacy and safety of Xuesaitong soft capsule combined with phacoemulsification in treating non-proliferative diabetic retinopathy (NPDR) and cataract. Methods: A total of 108 cases of patients with NPDR combinded cataract (116 eyes) who were admitted in our hospital from January 2015 to June 2015 were randomly divided into control group with 54 cases (57 eyes with cataract) and observation group with 54 cases (59 eyes with cataract). All patients were treated with conventional hypoglycemic therapy and phacoemulsification. The patients in the observation group were received Xuesaitong soft capsule additionally from 2 weeks before the operation to 3 months after operation. The effect of NPDR, the sight and average visual defect, the corneal scattered photometric and the complications of phacoemulsification and the drug adverse reaction were observed. Results: The total effective rate in the observation group was higher than that in the control group (P<0.05); both of the visual acuity and the visual field were continuously improved in 1 week and 3 months after operation in two groups (P<0.05), and the observation group was better (P<0.05); The corneal scattered photometric was significant increased in both two groups in 1 week after the operation significantly (P<0.05), while the corneal scattered photometric reduced back to preoperative in 3 months (P<0.05), and there were no difference between the two groups (P>0.05); and the complications of phacoemulsification of the observation group was lower than the control group (P<0.05). No adverse drug reactions were observed in both two groups. Conclusion: There was a good curative effect of Xuesaitong soft capsules combined with phacoemulsification in treating non-proliferative diabetic retinopathy (NPDR) and cataract, and it can improved the sight and average visual defect, and lower the complications of phacoemulsification. |
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