世界中医药
文章摘要
引用本文:刘娜,米娟,雒雪,艾广平.活血益肾法辅助治疗排卵障碍性不孕症患者疗效观察及对排卵的影响[J].世界中医药,2018,(01):.  
活血益肾法辅助治疗排卵障碍性不孕症患者疗效观察及对排卵的影响
Observation on the Curative Effects of Huoxue Bushen Decoction in the Treatment of Anovulatory Infertility and Effects on Ovulation
投稿时间:2017-05-03  
DOI:10.3969/j.issn.1673-7202.2018.01.025
中文关键词:  活血益肾法  排卵障碍性不孕症  疗效  排卵
English Keywords:Huoxue Bushen Decoction  Ovulation obstacle infertility  Curative effect  Ovulation
基金项目:中央高校基本科研业务费专项资金项目(310822171116)
作者单位
刘娜,米娟,雒雪,艾广平 延安市中医医院妇产科延安716000 
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中文摘要:
      目的:探讨活血益肾法辅助治疗排卵障碍性不孕症患者疗效观察及对排卵的影响。方法:选取2015年6月至2016年12月期间延安市中医医院收治的排卵障碍性不孕症患者96例,按照随机数字表法分为观察组48例与对照组48例。对照组于患者月经周期第5 d开始给予枸橼酸氯米芬胶囊,连续服用5 d;观察组在对照组基础上结合活血益肾法。2组患者疗程均为3个月经周期。比较2组治疗疗效,治疗前后血清激素水平、优势卵泡直径和子宫内膜厚度变化,以及成功排卵情况。结果:观察组治疗总有效率(89.58%)高于对照组(70.83%),且差异有统计学意义(P<0.05);2组治疗后血清E2水平增加(观察组t=24.739,对照组t=16.732,P<0.05),而LH、FSH水平降低(观察组t=27.483、12.144,对照组t=14.952、5.380,P<0.05);观察组治疗后血清E2水平高于对照组(t=9.276,P<0.05),而LH、FSH水平低于对照组(t=17.077、7.456,P<0.05);2组治疗后优势卵泡直径和子宫内膜厚度增加(观察组t=19.566、10.438,对照组t=15.348、6.103,P<0.05);观察组治疗后优势卵泡直径和子宫内膜厚度高于对照组(t=4.856、4.762,P<0.05);观察组成功排卵率(83.33%)高于对照组(64.58%),且有差异有统计学意义(P<0.05)。结论:活血益肾法辅助治疗排卵障碍性不孕症患者疗效显著,且可明显改善患者排卵情况。
English Summary:
      To investigate the effects of Huoxue Bushen Decoction in the treatment of anovulatory infertility and its effect on ovulation.Methods:A total of 96 cases of patients with anovulatory infertility treated in Yan'an traditional Chinese medicine hospital from June 2015 to December 2016 were randomly divided into observation group (n=48) and control group (n=48) according to random number table. The control group was given Clomifene Citrate Capsules at 5th day of menstrual cycle, with continuous use of 5d; the observation group was added Huoxue Bushen Decoction. Two groups of patients were treated for 3 menstrual cycles. The therapeutic effects of two groups were compared before and after treatment. The changes of serum hormone levels, the diameter of dominant follicles and the thickness of endometrium were observed before and after treatment. Results:The total efficiency of the observation group (89.58%) was higher than the control group (70.83%) (P<0.05); The serum level of E2 was increased after treatment in two groups (observation group t=24.739, control group t=16.732, P<0.05), and the levels of LH and FSH were decreased (observation group t=27.483,12.144, control group t=14.952, 5.380, P<0.05); the serum level of E2 after treatment in observation group was higher than the control group (t=9.276, P<0.05), and LH, FSH levels were lower than the control group (t=17.077, 7.456, P<0.05); the dominant follicle diameter and endometrial thickness of two groups after treatment were increased (observation group t=19.566, 10.438, control group t=15.348, 6.103, P<0.05); the dominant follicle diameter and endometrial thickness of the observation group after treatment was larger than the control group (t=4.856, 4.762, P<0.05); the successful ovulation rate of the observation group (83.33%) was higher than that of the control group (64.58%) (P<0.05). Conclusion:Huoxue Bushen Decoction is effective in the treatment of patients with anovulatory infertility, and can significantly improve the ovulation rate.
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