世界中医药

目的：探讨针灸治疗脑卒中抑郁症患者的疗效及对患者神经功能的影响。方法：选取2015年6月至2016年12月天津中医药大学第一附属医院收治的脑卒中抑郁症患者134例，按照随机表法分为观察组67例与对照组67例。对照组口服米氮平片，观察组在对照组基础上结合针灸治疗。2组疗程均为8周。比较2组治疗疗效，治疗前后NIHSS评分、HAMD评分、Balthel指数评分及血浆Cor和神经肽Y水变化。结果：观察组治疗有效率（95.52%）高于对照组（76.12%），差异有统计学意义（P<0.05）；2组治疗后NIHSS评分和HAMD评分降低，差异有统计学意义（P<0.05）；观察组治疗后NIHSS评分和HAMD评分低于对照组（P<0.05）；2组治疗后Balthel指数评分增加，差异有统计学意义（P<0.05）；观察组治疗后Balthel指数评分高于对照组（P<0.05）；2组治疗后血浆Cor降低而神经肽Y水平增加，差异有统计学意义（P<0.05）；观察组治疗后血浆Cor高于对照组，而神经肽Y水平低于对照组（P<0.05）。结论：针灸治疗脑卒中抑郁症患者疗效明显，且可改善患者神经功能，具有重要研究意义。

English Summary:

To investigate the efficacy of acupuncture treatment on stroke patients with depression and effects on neurological function. Methods:A total of 134 stroke patients with depression from First Hospital Affiliated to Tianjin Medical University from June 2015 to December 2016 were selected. They were randomly divided into observation group (n＝67) and control group (n＝67). The control group was treated with Mirtazapine Tablets, while the observation group was treated with acupuncture combined with the control group. The two groups were treated for 8 weeks. The therapeutic effects were compared between the two groups before and after treatment. The NIHSS score, HAMD score, Balthel index score and the changes of plasma Cor and neuropeptide Y were observed before and after treatment. Results:The total efficiency of the observation group (95.52%) was higher than the control group (76.12%) (χ2=10.364, P<0.05); the NIHSS score and HAMD score decreased in two groups after treatment, and there were significant differences (observation group, t＝17.890, 21.575, control group t＝10.243、9.808, P<0.05); NIHSS score and HAMD score in the observation group after treatment were lower than the control group (t＝9.557, 11.939, P<0.05); Balthel score of the two groups after treatment increased, and there were significant differences (observation group t＝24.793, control group t＝12.827, P<0.05); Balthel score of the observation group after treatment was higher than the control group (t＝11.333, P<0.05); plasma Cor levels decreased, and neuropeptide Y creased in two groups after treatment with statistical difference (observation group t＝10.089, 23.183, control group t＝5.388, 17.019, P<0.05); the plasma Cor of observation group after treatment was higher than the control group, while neuropeptide Y was lower than the control group (t＝5.388, 7.364, P<0.05). Conclusion:Acupuncture in the treatment of stroke patients with depression has significant curative effects, and can improve the neurological function of patients, with important research significance.

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