To study the effects of Qishen Huanwu Capsules combined with hydroxyethyl starch 130/0.4 on heart rate (HR), mean arterial pressure (MAP) and oxygen partial pressure for patients with posterior circulation ischemic vertigo (PCIV). Methods:A total of 120 cases of patients with PCIV were admitted and treated in Cangzhou Hospital of Integrated Chinese and Western Medicine from April 2015 to September 2016. According to random number table method, patients were divided into observation group (60 cases) and control group (60 cases). Patients in control group were treated with hydroxyethyl starch 130/0.4 and patients in observation group were treated with Qishen Huanwu Capsules on the basis of that in control group. Curative effects of the two groups were respectively compared after treatment--heart rate (HR), mean arterial pressure (MAP), oxygen partial pressure (PaO2) levels, the improvement of vertigo symptom before and after treatment as well as the change of the mean flow velocity (VM). Results:The total effective rate of the treatment group was 95.00% (57/60), which was higher than that of control group 81.67% (49/60) (P<0.05). HR, MAP, PaO2 levels in observation group after treatment were respectively (76.6±11.3) times/min, (91.2±10.4) mmHg and (81.4±12.6) mmHg, which were higher than those in control group (68.9±12.6) times/min, (81.7±11.5) mmHg, (73.2±12.8) mmHg, and had significant difference (P<0.05). DHI scores after treatment in two groups were lower than those before the treatment and the observation group were lower than those in control group, which had significant differences (P<0.05). After treatment, the left side of the vertebral artery VM, the right side of the vertebral artery VM and the basal artery VM in treatment group were higher than those in control group, with significant differences (P<0.05). Conclusion:Qishen Huanwu Capsules combined with hydroxyethyl starch 130/0.4 had significant effects on PCIV and can effectively maintain stable vital signs, decrease the effects of disease of patients and effectively improve the patients' blood rheology indexes.