| 引用本文:高轩1，王丽岳2，李洪林3，胡倩4.中西医结合内服外敷法治疗亚急性甲状腺炎的回顾性研究[J].世界中医药,2018,(02):. |
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| 中西医结合内服外敷法治疗亚急性甲状腺炎的回顾性研究 |
| Retrospective Study of Western Medicine Combined with Traditional Chinese Medicine Oral Administration and External Application in the Treatment of Subacute Thyroiditis |
| 投稿时间：2018-01-08 |
| DOI：10.3969/j.issn.1673-7202.2018.02.023 |
| 中文关键词: 中西医结合 内服外敷法 亚急性甲状腺炎 回顾性研究 |
| English Keywords:Integrated Chinese and Western medicine Oral administration and external application Subacute thyroiditis Retrospective study |
| 基金项目:湖北省自然基金项目(2010CDB8701) |
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| 中文摘要: |
| 目的：回顾性研究中西医结合内服外敷法治疗亚急性甲状腺炎的临床疗效。方法：选取2015年5月至2017年5月武汉市青山区普仁医院收治的经临床确诊的亚急性甲状腺炎患者64例，按照随机表法，随机分为中药组和对照组各32例。中药组采取中西医结合内服外敷法治疗，对照组采取单纯西医常规治疗。观察2组患者症状改善情况（甲状腺肿胀消退时间、甲状腺疼痛缓解时间以及退热时间）、理化指标（游离三碘甲状腺原氨酸、游离四碘甲状腺原氨酸、促甲状腺分泌激素、红细胞沉降率、C-反应蛋白）、复发情况、安全性指标和中医证候疗效。结果：中药组患者甲状腺肿胀消退时间、甲状腺疼痛缓解时间以及退热时间均低于对照组，差异有统计学意义（P<0.05）；2组治疗前与治疗后患者理化指标比较差异有统计学意义（P<0.05）；中药组治疗后与对照组治疗后患者理化指标比较差异有统计学意义（P<0.05）；中药组中医证候总有效率（93.75%）优于对照组（71.88%），差异有统计学意义（P<0.05）；中药组患者复发率（6.66%）明显低于对照组（21.74%），差异有统计学意义（P<0.05）；中药组患者激素相关性不良反应发生率（3.13%）明显低于对照组（15.63%），差异有统计学意义（P<0.05）。结论：中西医结合内服外敷法治疗亚急性甲状腺炎可以缩短病程，提高治疗效果，降低复发率，减少激素相关性不良反应，值得临床推广。 |
| English Summary: |
| To study the clinical effects of western medicine combined with traditional Chinese medicine oral administration and external application in the treatment of subacute thyroiditis.Methods:A total of 64 cases of subacute thyroiditis were admitted and treated by Puren Hospital of Wuhan City from May 2015 to May 2017.According to random table method,patients were randomly divided into treatment group and control group,with 32 cases in each group.The Chinese medicine group took western medicine combined with traditional Chinese medicine oral administration and external application,and the control group only took the conventional western medicine treatment.The improvement situations of patients in the two groups were observed including symptoms:thyroid swelling subside time,thyroid pain relief time and antipyretic time,physicochemical index:free triiodothyronine (FT3),free tetraiodothyronine (FT4),thyroid stimulating hormone (TSH),erythrocyte sedimentation rate (ESR).C-reactive protein (CRP),recurrence,safety index and efficacy of TCM syndromes.Results:The time of thyroid swelling subsided,the remission time of thyroid pain and the time of fever abatement in the TCM group were shorter than those in the control group,and the differences were statistically significant (P<0.05); The differences of physicochemical indexes of the two groups of patients before and after treatment were statistically significant (P<0.05); There were significant differences in physical and chemical indexes between the treatment group and the control group after treatment (P<0.05); The total effective rate of TCM syndrome of TCM group (93.75%) was better than that of control group (71.88%),and the difference was statistically significant (P<0.05); The recurrence rate of TCM group (6.66%) was significantly lower than that of the control group (21.74%),and the difference was statistically significant (P<0.05);The incidence rate of hormone related side reaction in TCM group (3.13%) was significantly lower than that in control group (15.63%),and the difference was statistically significant (P<0.05).Conclusion:Western medicine combined with traditional Chinese medicine treatment of subacute thyroiditis can shorten the course and improve the therapeutic effect,reduce the recurrence rate and reduce the hormone related adverse reaction,which was worthy of promotion in the clinic. |
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