Abstract:To compare the clinical effects and safety of Biantong Capsules and Qirong Runchang Oral Liquid in the treatment of patients with drug-induced constipation caused by antipsychotics.Methods:A total of 100 patients with schizophrenia were admitted and treated in Huairou Hospital of Traditional Chinese Medicine from October 2014 to August 2016.All the patients were prepared with constipation drugs.According to random number table,patients were randomly divided into two groups,the control group (Qirong Runchang Oral Liquid) and the observation group (Biantong Capsules).And the observation period and follow-up visit was for one year to observe the incidence of constipation,the constipation symptom score,total effective rate of constipation,average days of medicine taken and adverse reactions of the two groups' patients.Results:The constipation incidence of two groups had no significant difference (P>0.05); Cases that withdrawn from the study because of no relief of constipation for 3 days of treatment in the observation group were fewer than those in the control (P<0.05); The symptom score and average days of medicine taken were lower than those in the control group (P<0.05),while the cure-remarkable-effectiveness rate of constipation in the observation group was higher than that in the control group (P<0.05); And there was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion:Biantong Capsules and Qirong Runchang Oral Liquid were both effective in the treatment of constipation induced by antipsychotic,and the effects and safety of Biantong Capsules were better which was worthy of clinical promotion.