The strategy of “One Belt and One Road” brings new opportunities for the development of Traditional Chinese medicine (TCM) service trade. Based on the 4 modes of trade in services, such as Cross-border Supply, Consumption Abroad, Commercial Presence and Movement of Personnel, this paper summarized the current situation of TCM trade in China, analyzed the opportunities of “One Belt and One Road” for TCM trade, and gave some advices：Focus on the development of TCM medicine tourism; Develop TCM book industry and distance education firstly; Speed up the construction of overseas Chinese medicine institutions, Encourage private capital investment; Expand the scale of Chinese medicine talent export.