引用本文:朱音1,2,舒冰1,3,4,王拥军1,3,4,王晶1,3,4.骨质疏松症与阿尔茨海默病的相关性[J].世界中医药,2018,(02):. |
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骨质疏松症与阿尔茨海默病的相关性 |
Research Progress of the Correlation between Osteoporosis and Alzheimer's disease |
投稿时间:2017-03-15 |
DOI:10.3969/j.issn.1673-7202.2018.02.066 |
中文关键词: 骨质疏松 阿尔茨海默病 骨密度 淀粉样蛋白 |
English Keywords:Osteoporosis Alzheimer disease Bone density Amyloid |
基金项目:国家科技部重点领域“创新团队”(2015RA4002);国家教育部“创新团队发展计划”(IRT1270) |
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中文摘要: |
骨质疏松症(Osteoporosis,OP)是一种以骨量低下、骨微结构破坏,导致脆性骨折的退行性骨病。阿尔茨海默病(Alzheimer's Disease,AD)主要表现为记忆力减退和认知功能障碍。表面上看OP和AD不论是在症状还是在体征方面都截然不同,但越来越多的研究表明两者存在一些共有的致病因素、发病机制和信号通路。 |
English Summary: |
Osteoporosis (OP) can be defined as a degenerative bone disease characterized by low bone mass and the microarchitectural deterioration, with a consequent increase in the fragility of bone and susceptibility to fracture. Alzheimer's disease (AD) is a disease with memory loss and cognitive impairment. Despite their different signs and symptoms, these two diseases share many common risk factors, pathogenesis and signaling pathways. |
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