世界中医药
文章摘要
引用本文:陈爱玲,马丛丛,刘存勇.补阳还五汤治疗脑卒中的临床疗效及对患者血液流变学的影响[J].世界中医药,2018,(03):.  
补阳还五汤治疗脑卒中的临床疗效及对患者血液流变学的影响
Clinical Efficacy of Buyang Huanwu Decoction in the Treatment of Stroke and Influence on Hemorheology
投稿时间:2017-05-02  
DOI:10.3969/j.issn.1673-7202.2018.03.020
中文关键词:  脑卒中  补阳还五汤  神经功能缺损  血液流变学  疗效
English Keywords:Stroke  Buyang Huanwu decoction  Neurologic impairment  Hemorheology  Efficacy
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作者单位
陈爱玲,马丛丛,刘存勇 清华大学附属北京市垂杨柳医院北京100022 
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中文摘要:
      目的:探究补阳还五汤治疗脑卒中的临床疗效,分析其对患者神经功能缺损改善情况及对血液流变学的影响。方法:选取2014年2月至2016年9月清华大学附属北京市垂杨柳医院收治的脑卒中患者200例,随机分为对照组及观察组,各100例。对照组给予常规西医治疗,观察组在对照组的基础上联合补阳还五汤治疗,4周为1个疗程,2组均连续治疗2个疗程。统计2组临床疗效,判定并比较2组治疗前后美国国立卫生研究院卒中量表(NIHSS)评分及Barthel评分,对比2组致残情况;于治疗前后检测并比较2组血液流变学指标。结果:观察组临床总有效率为9400%,高于对照组的6700%(P<005);与治疗前比较,治疗后2组NIHSS评分降低,且观察组低于对照组(P<005);2组Barthel评分均升高,且观察组高于对照组(P<005);与治疗前比较,治疗后2组0、1、2级致残患者比例明显升高(P<005),2组4级致残患者比例及观察组5级致残患者比例降低(P<005);2组致残级别<4级的患者比例升高(P<005),且观察组高于对照组(P<005);与治疗前比较,治疗后2组全血低切黏度、红细胞聚集指数及观察组全血高切黏度、血浆黏度降低(P<005),且观察组上述指标低于对照组(P<005)。结论:补阳还五汤可有效改善脑卒中患者神经功能缺损及血液流变学,提高临床疗效。
English Summary:
      To explore the clinical effect of Buyang Huanwu decoction in the treatment of stroke, and to analyze the improvement of neurologic impairment and the influence on hemorheology. Methods:A total of 200 cases of stroke patients who were treated in our hospital from February 2014 to September 2016, and were randomly divided into control group and treatment group, with 100 cases in each group. The control group was treated with conventional western medicine treatment, and treatment group was treated combined with Buyang Huanwu decoction based on the control group, with 4 weeks as 1 treatment course. Both groups were treated for 2 courses continuously. The clinical efficacy of 2 groups was evaluated, and the NHISS score and Barthel score were determined and compared. The disabling conditions of 2 groups were compared. Besides, the hemorheology indexes before and after treatment was detected and compared. Results:The clinical total effective rate (9400%) in treatment group was higher than the control group (6700%) (P<001). Compared with before treatment, the NIHSS scores of 2 groups decreased significantly, and the treatment group was lower than that of control group (P<005). The Barthel scores of 2 groups increased significantly, and the treatment group was higher than that of control group (P<005). Compared with that before treatment, the proportion of 0, 1, 2 class disabled patients in 2 groups increased significantly (P<005 or P<001), while the proportion of 4 class disabled patients in 2 groups and the proportion of 5 class disabled patients in treatment group decreased significantly (P<005 or P<001). The proportion of disability level
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