世界中医药
文章摘要
引用本文:郜朝霞,邵力伟,陈春洲.小金胶囊配合手术治疗瘘管期浆细胞性乳腺炎的疗效观察[J].世界中医药,2018,(03):.  
小金胶囊配合手术治疗瘘管期浆细胞性乳腺炎的疗效观察
Efficacy Observation on Xiaojin Capsule Combined With Surgical Operation in the Treatment of Plasma Cell Mastitis in Period of Fistula
投稿时间:2018-01-10  
DOI:10.3969/j.issn.1673-7202.2018.03.027
中文关键词:  浆细胞性乳腺炎  瘘管期  小金胶囊  复发率
English Keywords:Plasma cell mastitis  Fistula stage  Xiaojin Capsule  Recurrence rate
基金项目:
作者单位
郜朝霞,邵力伟,陈春洲 武汉市第五医院武汉430053 
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中文摘要:
      目的:观察小金胶囊联合手术治疗瘘管期浆细胞性乳腺炎的疗效与安全性。方法:选取2011年3月至2015年4月武汉市第五医院收治的浆细胞性乳腺炎瘘管期患者96例,随机分为观察组和对照组,每组48例。对照组给予常规手术治疗,观察组在对照组的基础上加服小金胶囊。观察术后7 d时伤口愈合率,不良事件发生率,随访术后6个月,12个月,24个月时的复发率。结果:观察组有2例在第12个月时失访,5例在24个月时失访,对照组有1例在第12个月时失访,3例在24个月时失访。术后7 d时,观察组愈合率979%,对照组愈合率854%,观察组显著优于对照组(P<005);术后6个月,12个月,24个月回访中,观察组复发率分别为0%,43%,70%;对照组复发率分别为83%,170%和222%,观察组复发率显著低于对照组(P<005)。未观察到与药物有直接相关的不良反应。结论:瘘管期浆细胞性乳腺炎在围手术期服用小金胶囊,能提高创口愈合率,降低复发率,安全性良好。
English Summary:
      To observe the clinical effects and safety of Xiaojin Capsule combined with surgical operation in the treatment of plasma cell mastitis in period of fistula. Methods:A total of 96 cases of patients with plasma cell mastitis in period of fistula who were treated in our hospital from March 2011 to April 2015 were selected and randomly divided into observation group and control group, with 48 cases in each group. The patients were treated with conventional surgery in the control group, while the observation group was treated with Xiaojin capsules on the basis of the control group. The rate of wound healing and the incidence of adverse events were observed in 7th days post operation. And the recurrence rate was followed up at 6th month, 12th month and 24th month after operation. Results:Two cases were lost follow up at the 12th month post operation in observation group, and 5 cases in 24th month, while only 1 case was lost follow up at the 12th month, and 3 cases at 24th month in the control group. The healing rate of the observation group was 979% on the 7th day after operation, which was significantly higher than that of the control group (P<005), while that of the control group was 854%. The recurrence rate of the observation group was respectively 0%, 43% and 70% on the 6th month, 12th month and 24th month after operation, which was significantly higher than that of the control group (P<005), while that of the control group was 83%, 170% and 222% respectively. No adverse reactions were observed directly related to the Xiaojin Capsule. Conclusion:Xiaojin capsule can significantly improve the wound healing rate, reduce the recurrence rate in the treatment of fistula stage plasma cell mastitis in the perioperative period, while its safety is favorable.
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