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引用本文:李嘉慧，欧妍.定坤丹结合激素治疗肾虚肝郁证月经过少患者的临床疗效及对子宫内膜厚度的影响[J].世界中医药,2018,(03):.

定坤丹结合激素治疗肾虚肝郁证月经过少患者的临床疗效及对子宫内膜厚度的影响

Clinical Efficiency of Dingkun Pellet Combined with Hormone in the Treatment of Patients with Hypomenorrhea of Kidney Deficiency Liver Depression Type and the Influence on the Endometrium

投稿时间：2017-09-01

DOI：10.3969/j.issn.1673-7202.2018.03.031

中文关键词: 月经过少激素定坤丹肾虚肝郁证临床疗效子宫内膜月经量厚度

English Keywords:Hypomenorrhea Hormone Dingkun Pellet Kidney deficiency and liver depression type Clinical efficiency Endomembrane Menstrual blood volume Thickness

基金项目:北京市属医院科研培训计划项目(PZ2017003）

作者	单位
李嘉慧，欧妍	北京中医医院顺义医院妇产科，北京，101300

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中文摘要:

目的：探究定坤丹结合激素治疗肾虚肝郁证月经过少患者的临床疗效及对子宫内膜厚度的影响。方法：选取2011年1月至2015年5月北京中医医院顺义医院妇科门诊收治的确诊为肾虚肝郁证月经过少女性患者300例，随机分为对照组和观察组，每组150例。2组患者同时予雌孕激素周期治疗，观察组在此基础上予定坤丹治疗；连续治疗2个月经周期为１个疗程。共服2个疗程。结果：治疗后2组月经量、子宫内膜厚度、血清LH、E2及P水平与治疗前相比显著增加，行经时间显著延长（P<005）；且观察组变化幅度均显著大于对照组（P<005）；治疗后观察组总有效率为9043%，显著高于对照组的6457%（P<005）。结论：定坤丹结合激素与单纯应用激素相比治疗肾虚肝郁证月经过少患者可以获得更好的治疗效果，可以明显增加患者的月经量、行经时间、性激素水平、子宫内膜厚度。

English Summary:

To investigate the clinical efficiency of Dingkun Pellet combined with hormone in the treatment of patients with hypomenorrhea of kidney deficiency and liver depression type and the influence on the endometrium. Methods:A total of 300 patients with hypomenorrhea of kidney deficiency and liver depression type who were treated in our hospital from January 2011 to January 2015 were selected and randomly divided into control group and test group, with 150 cases in each group. Both groups received the regular estrogen and progestin hormone treatment, and the test group added Dingkun Pellet. One treatment course included 2 menorrhea circle time, and the treatment lasted 2 courses. Results:After treatment, the menorrhea blood quality, menorrhea lasting time, endometrium thickness and serum LH, E2 and P levels of the 2 groups all increased significantly (P<00 5or P<001), and the rangeability in the test group was significant larger than the control group (P<001). The total effective rate was 9043%, which was higher than that 6457% of control group (P<001). Conclusion:The clinical efficiency of Dingkun Pellet combined with hormone in the treatment of patients with hypomenorrhea of kidney deficiency and liver depression type is better than sex hormone alone, which can outstandingly increase menorrhea blood quality, menorrhea lasting time, endometrium thickness and sex hormone levels.

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