| 引用本文:孙亚涛，冯淑兰.温针灸辅助治疗对膝关节炎患者的预后影响研究[J].世界中医药,2018,(04):. |
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| 温针灸辅助治疗对膝关节炎患者的预后影响研究 |
| Study on the Prognostic Effect of Warm Acupuncture and Moxibustion Assisted Treatment for Patients with Knee Osteoarthritis |
| 投稿时间：2018-01-01 |
| DOI：10.3969/j.issn.1673-7202.2018.04.041 |
| 中文关键词: 温针灸 膝关节骨性关节炎 炎性反应细胞因子 关节积液 骨关节炎指数评分 |
| English Keywords:Warm acupuncture moxibustion Knee osteoarthritis Inflammatory factors Hydrops articuli WOMAC score |
| 基金项目:广东省科技计划项目专题(20140221)——“蜂针治疗类风湿性关节炎的临床标准化方案研究” |
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| 中文摘要: |
| 目的:探讨温针灸辅助抗炎止痛药、软骨保护剂治疗膝关节炎的作用机制及其对患者预后的影响。方法:选取2015年10月至2017年5月广州中医药大学针灸康复临床医学院收治的膝骨关节炎患者126例，按随机数字表法分为观察组和对照组，每组63例。观察组采用“扶他林+维固力”药物联合温针灸治疗；对照组采用“扶他林+维固力”药物治疗。比较2组的疗效、关节滑液炎性反应因子水平、关节积液深度及滑膜厚度、WOMAC评分变化情况。结果:观察组的总有效率93.65%明显高于对照组的80.95%，差异有统计学意义（P<0.05）；观察组治疗后的关节液中IL-1、TNF-α、MMP-3水平明显低于对照组，差异有统计学意义（P<0.05）；观察组治疗后的关节积液明显少于对照组、且滑膜厚度明显优于对照组，差异有统计学意义（P<0.05）；观察组治疗后的WOMAC总积分及各单项评分均明显低于对照组，差异有统计学意义（P<0.05）。结论:温针灸能温通经络、行气活血、祛瘀止痛，临床辅助药物治疗膝关节炎可以减轻炎性反应，促进关节积液吸收，有助于改善膝关节功能。 |
| English Summary: |
| To investigate the mechanism of warm acupuncture moxibustion combined with anti-inflammatory analgesics and cartilage protective agents in the treatment of knee osteoarthritis and its prognostic impact of patients with knee.Methods:A total of 126 cases of patients admitted to our hospital from October 2015 to May 2017 were enrolled in the study and randomly divided into the group I and the groupⅡ according to random number table，with 63 cases in each group.The group I was received the treatment plan of warm acupuncture moxibustion combined with voltaren and viartril-S，and groupⅡ was only given warm acupuncture moxibustion.The curative effect，joint fluid inflammatory factors，joint effusion depth，synovial thickness and WOMAC score in two groups were observed and compared.Results:The total effective rate in the group I was significantly higher than that in the groupⅡ(93.65% vs 80.95%，P<0.05)； the levels of IL-1，TNF-αand MMP-3 in joint fluid after treatment in the group I were significantly lower than those in the groupⅡ (P<0.05); the joint effusion in the group I was significantly less than that in the groupⅡ，and the synovial thickness was significantly better than that in the groupⅡ (P<0.05); the total scores of WOMAC and its individual items in the group I were significantly lower than those in the groupⅡ (P<0.05).Conclusion:Warm acupuncture moxibustion can warm the channels and collaterals，invigorate qi and the circulation of blood，relieve blood stasis and pain.The combination with drugs in the treatment of knee osteoarthritis can reduce inflammation，promote the absorption of joint fluid and help improve the function of the knee joint. |
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