世界中医药

作者	单位
李亚天1，贾弘晓2，郭霞珍1，王彤1	1 北京中医药大学，北京，100029； 2 首都医科大学附属北京安定医院，北京，100088

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中文摘要:

目的:从五运六气来探究重性抑郁和双相情感障碍发病时间和形式规律，为抑郁症的的预防性治疗提供新的思路方法。方法:收集了从2014年1月至2015年2月北京安定医院的重性抑郁和双相情感障碍181名患者为研究对象。根据每次发病时间推算五运六气因素，包括岁运、主运、主气、客运、客气，得出发病的五运六气规律，以及抑郁相和躁狂相各自五运六气规律。结果：主运：重性抑郁禀赋为水者易发作在木运。双相情感障碍禀赋为水、金、火、土，皆易在火运发为躁狂。客运：重性抑郁禀赋为木者，易发作在木运。双相情感障碍患者中，禀赋为木的患者，更容易在土运发为抑郁或躁狂。主气：重性抑郁禀赋为阳明燥金者，易发作在阳明燥金。双相情感障碍患者中，禀赋为厥阴风木的患者，更容易在少阴君火发为抑郁而阳明燥金发为躁狂。禀赋为少阴君火的患者，更容易在阳明燥金发为抑郁而厥阴风木发为躁狂。禀赋为阳明燥金和太阳寒水者，皆易在厥阴风木发为抑郁，君火或相火之气发为躁狂。客气：重性抑郁禀赋为少阳相火者，最不易发作在太阳寒水。而双相情感障碍禀赋少阳相火者易发作太阳寒水，重性抑郁和双相情感障碍形成显著差异。结论：本研究认为禀赋和发病时间具有相关性，且重性抑郁和双相情感障碍各个禀赋的发病比较，差异有统计学意义（P=0.00<0.01），双相情感障碍抑郁相和躁狂相各个禀赋的发病比较，差异有统计学意义（P=0.00<0.01）。

English Summary:

To explore occurrence law of major depression and bipolar disorder based on theory of five circuits and six qi, and provide a new thoughts and methods to future study on preventive treatment of depression. Methods:Data of 181 patients with major depression and bipolar disorder in our hospital from January 2014 to February 2015 were collected. The occurrence date were converted into five circuits and six qi, including year evaluative phase, host evaluative phase, host climate qi, guest evaluative phase and guest climate qi, and we concluded occurrence law of affective disorder, and separately of major depression and bipolar disorder. Results:Host evaluative phase: Major depression reached maximum on water of endowment, on wood of outbreak, and it got its minimum on metal of endowment, on earth of outbreak. Bipolar disorder reached maximum on water of endowment, on fire of outbreak, and it got its minimum on earth of endowment, on water of outbreak. Guest evaluative phase: Major depression reached maximum on wood of endowment, on wood of outbreak. Bipolar disorder reached maximum on wood of endowment, on earth of outbreak. Host climatic qi: Major depression reached maximum on yangming dryness metal of endowment, on yangming dryness metal of outbreak, Bipolar disorder reached maximum on taiyang cold water of endowment, on shaoyin chief fire of outbreak, or on taiyin water earth of endowment, on yangming dryness metal of outbreak, and it got its minimum on jueyin wind wood of endowment, on jueyin wind wood of outbreak. Guest climatic qi: Major depression reached its minimum on shaoyang phase fire of endowment, on taiyang cold water of outbreak. Bipolar disorder reached maximum on shaoyang phase fire of endowment, on taiyang cold water of outbreak. Conclusion:There was correlation between endowment and outbreak of depression, and difference between outbreak of major-depression and bipolar-disorder endowments was significant (P=0.00<0.01), as was difference between bipolar disorder outbreak of depressive-state and manic-state endowment (P=0.00<0.01).

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