世界中医药
文章摘要
引用本文:孙莺.健脾宣肺防喘汤对缓解期哮喘患儿气道反应性及哮喘控制的影响[J].世界中医药,2018,(05):.  
健脾宣肺防喘汤对缓解期哮喘患儿气道反应性及哮喘控制的影响
Effects of Jianpi Xuanfei Fangchuan Decoction on Airway Responsiveness and Asthma Control in Children with Asthma at Remission Stage
投稿时间:2016-05-21  
DOI:10.3969/j.issn.1673-7202.2018.05.036
中文关键词:  哮喘  糖皮质激素  健脾宣肺防喘汤  气道高反应性
English Keywords:Asthma  Glucocorticoid  Jianpi Xuanfei Fangchuan Decoction  Airway high reactivity
基金项目:
作者单位
孙莺 南方医科大学附属深圳市宝安区人民医院中医科,深圳,518101 
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中文摘要:
      目的:探讨健脾宣肺防喘汤对缓解期哮喘患儿气道反应性及哮喘控制的影响。方法:选取2014年4月至2015年4月南方医科大学附属深圳市宝安区人民医院收治的哮喘缓解期患儿70例,随机分为2组,对照组予吸入糖皮质激素治疗,观察组在此基础上联合应用自拟健脾宣肺防喘汤治疗,于治疗前后对2组患儿进行肺功能及支气管激发试验检查,测定第1秒用力呼气量(FEV1)下降20%时组胺累计剂量(PD20),并于治疗结束后随访12个月,比较治疗前及随访结束时儿童哮喘控制测试(C-ACT)评分情况。结果:治疗后,2组患儿PD20、FEV1和呼气峰流速(PEF)均有显著提高,但观察组患儿明显高于对照组,差异有统计学意义(P<0.05);随访12个月,观察组患儿哮喘完全控制率及C-ACT评分均明显高于对照组,差异有统计学意义(P<0.05)。结论:健脾宣肺防喘汤能够降低哮喘患儿气道高反应性,改善哮喘控制水平。
English Summary:
      To investigate the effects of Jianpi Xuanfei Fangchuan Decoction on airway responsiveness and asthma control in children with asthma at remission stage. Methods:A total of 70 cases of children with asthma treated from April 2014 to April 2015 were randomly divided into two groups. The control group was treated with inhaled glucocorticoid therapy, and the observation group was combined with Jianpi Xuanfei Fangchuan Decoction based on that treatment. The pulmonary function and bronchial provocation test, the second histamine cumulative dose (PD20) of forced expiratory volume in 1 second (FEV1) 20% falling was detected before and after treatment. After followed up for 12 months, Childhood Asthma Control Test (C-ACT) was compared with before the treatment in both groups. Results:After treatment, the PD20, FEV1 and peak expiratory flow (PEF) were significantly increased in both groups, but that in the observation group were significantly higher than those in the control group. The difference was statistically significant (P<0.05); After 12 months of follow-up, the asthmatic complete control rate and C-ACT scores were significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion:The Jianpi Xuanfei Fangchuan Decoction can reduce bronchial high reactivity in children with asthma, and improve the asthma control.
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