| 引用本文:夏尔巴提·吾马尔1，金小越2.莲威阿那其颗粒剂抗炎镇痛作用的实验研究[J].世界中医药,2018,(05):. |
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| 莲威阿那其颗粒剂抗炎镇痛作用的实验研究 |
| Experimental Study on Anti-inflammatory and Analgesic Effects of Lianwei Anaqi Granules |
| 投稿时间：2018-01-12 |
| DOI：10.3969/j.issn.1673-7202.2018.05.039 |
| 中文关键词: 莲威阿那其颗粒剂 抗炎 镇痛 小鼠 耳廓肿胀法 实验研究 |
| English Keywords:Lianwei Anaqi granules Anti-inflammatory Analgesic Mice Ear swelling test Experimental study |
| 基金项目:新疆维吾尔自治区科技支疆项目(201191257) |
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| 中文摘要: |
| 目的:研究莲威阿那其颗粒剂对小鼠抗炎及镇痛作用。方法:采用小鼠热板法和醋酸扭体法,检测莲威阿那其颗粒剂的镇痛作用。采用小鼠耳廓肿胀法观察莲威阿那其颗粒剂的抗炎作用。小鼠随机分为5组,即空白对照组、莲威阿那其颗粒剂高、中、低剂量组、阿司匹林组。每组小鼠连续灌胃给药7 d后,观察莲威阿那其颗粒剂的抗炎、镇痛作用。结果:莲威阿那其颗粒剂能明显抑制二甲苯所致的小鼠耳廓肿胀,中、高剂量明显提高小鼠的痛阈,对小鼠醋酸扭体法和热板法致痛反应有较好的止痛作用。结论:莲威阿那其颗粒剂有明显的抗炎、镇痛疗效。 |
| English Summary: |
| To investigate the anti-inflammatory and analgesic effects of Lianwei Anaqi granules. Methods:The analgesic effect of Lianwei Anaqi granules was determined by hot plate test and acetic acid writhing test in mice. The anti-inflammatory effect of Lianwei Anaqi granules was observed by ear swelling test in mice. Mice were divided into 5 groups randomly, namely blank control group, Lianwei Anaqi granules at high, medium and low doses groups, and Aspirin group. The anti-inflammatory and analgesic effects of Lianwei Anaqi granules were observed after every group mice were orally given correspondence durg (ig) for 7 days. Results:Lianwei Anaqi granules could inhibit ear swelling caused by Xylene in mice markedly, and the high and medium doses of Lianwei Anaqi granules could increase pain threshold significantly. In the acetic acid writhing test and hot plate test, Lianwei Anaqi granules showed greater analgesic effects. Conclusion:Lianwei Anaqi granules have significant anti-inflammatory and analgesic effects. |
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