To evaluate the therapeutic effect and safety of removing the necrotic tissue and promoting granulation method in the treatment non-puerperal mastitis in the late stage of ulceration.Methods:A total of 60 patients with non-puerperal mastitis in the late stage of ulceration from Jan 2016 to Des 2017, and randomly divided them into treatment group and control group.The treatment group was given Badu Shengji powder and cankerous oily regional treatment and oral medicine,and the control group was treated with silver ion antibacterial materials surgical treatment and oral medicine treatment.The treatments last for 12 weeks.The collected data were analyzed to evaluate the clinical efficacy and safety.Results:The treatment group recovered 25 cases,accounting for 93.3%,and 2 cases showed significant curative effect,which accounted for 6.7%,and the average healing time was (7.3±0.16) weeks.In the control group,21 cases were cured,accounting for 70%,3 cases showed significant curative effect,accounting for 10%,and 6 cases were improved,accounting for 20%,and the mean healing time was (9.6±0.77) weeks.There were statistical differences (P<0.05).In addition,the healing time,the area change of the ulcer,and the change of sinus depth of two groups after treatment were also statistically significant (P<0.05).There were no significant differences in the breast appearance score,local lump in breast diameter change (P>0.05).There were no patients with liver and kidney dysfunction during the treatment.Conclusion:Application of Badu Shengji powder and cankerous oily regional treatment of removing the necrotic tissue and promoting granulation method in the treatment of non-puerperal mastitis in the late stage of ulceration can promote healing of the dyke,reduce breast pain,shorten the healing time,improve curative effect,and the treatment is effective and feasible. |