| 引用本文:陶智军，刘晓辉.养肾补心汤对病毒性心肌炎患者血清炎性反应因子、心肌酶谱的影响[J].世界中医药,2018,(06):. |
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| 养肾补心汤对病毒性心肌炎患者血清炎性反应因子、心肌酶谱的影响 |
| The Influence of yangshen buxin Tang on Serum Inflammatory Factors and Myocardial Enzyme Spectrum of Patients with Viral Myocarditis |
| 投稿时间：2018-04-11 |
| DOI：10.3969/j.issn.1673-7202.2018.06.026 |
| 中文关键词: 病毒性心肌炎 养肾补心汤 炎性反应因子 心肌酶谱 |
| English Keywords:Viral myocarditis Yangshen buxin decoction Inflammatory factor Myocardial enzyme spectrum |
| 基金项目:湖北省科学技术厅科技攻关计划项目(EK2016D170048001260) |
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| 中文摘要: |
| 目的:探讨养肾补心汤对病毒性心肌炎(VMC)患者血清炎性反应因子、心肌酶谱的影响。方法:选取2015年10月至2017年8月武穴市第二人民医院收治的VMC患者126例,按照治疗方法的不同分为观察组(n=62)和对照组(n=64)。对照组采用常规西药治疗,观察组在对照组的基础上加用养肾补心汤治疗,2组均连续治疗2个月。比较2组临床疗效、治疗前后血清炎性反应因子及心肌酶谱指标水平;记录治疗过程中2组不良反应发生情况。结果:治疗后观察组与对照组总有效率分别为90.32%、75.00%,观察组显著高于对照组(P<0.05);与治疗前比较,治疗后2组血清IL-6、IL-9、IL-17及TNF-α水平显著下降,且观察组显著低于对照组(P<0.01);2组血清IL-27水平显著升高,且观察组显著高于对照组(P<0.01);与治疗前比较,治疗后2组血清AST、LDH、CK、CK-MB水平均显著下降,且观察组显著低于对照组(P<0.01);治疗期间观察组恶心、呕吐、及腹泻的发生率显著低于对照组(P<0.05)。结论:养肾补心汤治疗VMC可有效降低患者血清炎性反应因子及心肌酶谱指标水平,显著提升临床疗效。 |
| English Summary: |
| To investigate the influence of yangshen buxin Tang on serum inflammatory factors and myocardial enzyme spectrum of patients with viral myocarditis ( VMC ).Methods:A total of 126 cases of VMC patients in our hospital were selected and divided into the observation group ( n=62 ) and the control group ( n=64 ),according to the different treatment methods.The control group was treated with conventional western medicine treatment,and the observation group was added with yangshen buxin Tang,on the basis of control group.The 2 groups were treated for 2 months.The clinical effects,serum inflammatory factors and myocardial enzyme spectrum indexes levels before and after treatment of the 2 groups were compared and the adverse reaction in the course of treatment of 2 groups were recorded.Results:The total effective rate of observation group and control group after treatment were 90.32% and 75.00% respectively,and the observation group was significantly higher than control group ( P<0.05 ).Compared with those before treatment,the levels of serum IL-6,IL-9,IL-17 and TNF-α of 2 groups after treatment significantly decreased,and observation group was significantly lower than control group ( P<0.01 ).The levels of serum IL-27 of 2 groups after treatment significantly increased,and observation group was significantly higher than control group ( P<0.01 ); compared with before treatment,the levels of serum AST,LDH,CK,CK-MB of 2 groups after treatment significantly decreased,and observation group was significantly lower than control group (P<0.01); the incidence of nausea,vomiting and diarrhea of observation group was significantly lower than those of control group (P<0.05).Conclusion Yangshen buxin decoction in the treatment of VMC patients can effectively reduce the level of serum inflammatory factors and myocardial enzyme spectrum,indexes,improve the clinical curative effect. |
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