世界中医药
文章摘要
引用本文:张爽,刘治飞,高洁,问娟娟.陕产瞿麦中总黄酮提取工艺响应曲面法的优化[J].世界中医药,2018,(06):.  
陕产瞿麦中总黄酮提取工艺响应曲面法的优化
Study on Optimization of Total Flavonoids of Herba Dianthi from Shaanxi in the Extraction Process by Response Surface Method
投稿时间:2017-06-30  
DOI:10.3969/j.issn.1673-7202.2018.06.056
中文关键词:  陕产瞿麦  黄酮类化合物  超声提取  响应曲面法  单因素试验  紫外可见分光光度法  工艺条件  提取率
English Keywords:Herba Dianthi in Shaanxi Province  Flavonoids  Ultrasonic extraction  Response surface method  Single factor test  UV visible spectrophotometry  Process conditions  Extraction rate
基金项目:陕西省教育厅2017年专项科学研究计划(17JK0944);2016年陕西省大学生创新创业训练计划项目(2955);陕西国际商贸学院校级科研课题(SMXY201629)
作者单位
张爽,刘治飞,高洁,问娟娟 陕西国际商贸学院医药学院西安712046 
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中文摘要:
      目的:评价响应曲面法优选出超声辅助提取陕产瞿麦中总黄酮类化合物的最优方案。方法:实验以陕产瞿麦为原料,乙醇为提取剂,在单因素实验的基础上,通过响应面实验对超声辅助法提取陕产瞿麦中总黄酮的工艺进行优化。结果:优选出了超声辅助提取陕产瞿麦中总黄酮的最佳工艺条件:液料比10倍、提取功率140 W、乙醇浓度80%时,总黄酮的提取率最大可以达到0.851%。结论:工艺的实验值与预测值基本相符,采用响应曲面法优选超声辅助提取陕产瞿麦中黄酮类化合物的提取工艺稳定可行,为陕产瞿麦资源的开发和利用提供一定的参考依据。
English Summary:
      To select the optimized plan of ultrasonic assisted extracting total flavonoids in Herba Dianthi from Shaanxi by the response surface method.Methods:In this experiment, Shaanxi producing Herba Dianthi was taken as raw material, and ethanol as extraction agent.On the basis of single factor experiment, the extraction process of total flavonoids from Herba Dianthi of Shaanxi by ultrasonic assisted method was optimized with the response surface method.Results:The ultrasonic assisted extraction conditions of total flavonoids in Herba Dianthi from Shaanxi were optimized:liquid and material ratio was 10 times, extraction power 140W, 80% ethanol concentration, and the extraction rate of flavonoids could reach 0.851%.Conclusion:The process of the experimental values are basically consistent with the predicted value, indicating using response surface methodology to optimize ultrasonic assisted extraction technology of flavonoids in Herba Dianthi in Shaanxi Province is stable and feasible, and providing reference for the development and utilization of Herba dianthi resources in Shaanxi Province.
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