| 引用本文:李志强1，刘凤新2，何玉霞3.中西医结合治疗耐多药肺结核的疗效及对患者免疫功能的影响[J].世界中医药,2018,(07):. |
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| 中西医结合治疗耐多药肺结核的疗效及对患者免疫功能的影响 |
| Efficacy of Integrated Traditional Chinese and Western Medicine in the Treatment of Multi-drug Resistant Tuberculosis and Its Influence on Patients' Immune Function |
| 投稿时间：2017-04-13 |
| DOI：10.3969/j.issn.1673-7202.2018.07.011 |
| 中文关键词: 中西医结合治疗 耐多药肺结核病患者 疗效 免疫功能 |
| English Keywords:Combined traditional Chinese and western medicine treatment Multi-drug resistant tuberculosis patients Curative effects Influence of immune function |
| 基金项目:沧州市科学技术研究与发展指导计划项目（162302097）——穴位手法注射卷曲霉素与莫西沙星联合治疗耐多药肺结核的疗效观察 |
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| 中文摘要: |
| 目的：探讨中西医结合治疗耐多药肺结核的疗效及对患者免疫功能的影响。方法：选取2014年2月至2017年1月沧州市传染病医院检查就诊的耐多药肺结核病患者120例，随机分成观察组和对照组，每组60例，观察组采用中西医结合治疗，对照组单纯采用西药治疗，比较2组患者的临床效果；结果：2组患者经过相应的方法进行治疗数个月后，观察组总有效率高于对照组（P<0.05），2组患者在治疗4个月、7个月、10个月和13个月后，观察组患者的病灶吸收情况明显优于对照组，差异有统计学意义(P<0.05)。随着治疗时间的递增，2组患者的转阴率也逐渐呈递增的态势；治疗4个月、7个月、10个月和13个月后，观察组转阴率分别为55.00%、76.67%、86.67%、91.67%，观察组同一时间的痰结核分枝杆菌转阴率明显高于对照组，差异有统计学意义(P<0.05)；结论：中西医结合治疗总有效率、病灶吸收情况、转阴率等方面优于单纯采用西药治疗。 |
| English Summary: |
| To investigate the curative effects of integrated traditional Chinese and western medicine treatment of multi-drug resistant tuberculosis and influence on patients' immune function.Methods:A total of 120 cases of multi-drug resistant tuberculosis patients in our hospital from February 2014 to January 2017 were selected and randomly divided into observation group and control group，with 60 cases in each group.The observation group was treated by combining Chinese and western medicine treatment，and the control group was treated only with western medicine.The clinical effect of two groups of patients were observed and compared.Results:After corresponding treatment method for a few months，the total effective rate of observation group was significantly higher than that of the control group，and the differences were statistically significant (P<0.05).After treatment for 4 months，7 months，10 months and 13 months，the lesions absorption of observation group was significantly better than the control group，and the differences were statistically significant (P<0.05).After a period of treatment，the extension of treatment time，turn rate of two groups of patients were increasing，showing that two groups of patients had certain improvement.After treatment for 4 months，7 months，10 months and 13 months，the turn rates of observation group patients were 55.00%，76.67%，86.67%，91.67% respectively.The turn rate of sputum mycobacterium tuberculosis of observation group was significantly higher than that of control group in the same time，and the differences were statistically significant (P<0.05).Conclusion:The syndrome differentiation of traditional Chinese medicine and western medicine diagnosis is used in treating multi-drug resistant tuberculosis.Chinese medicine treats the root causes，and western medicine tends to alleviate the symptoms，and they give full play to their respective advantages and make up for the shortage.The idea of integrated Chinese and western medicine has been popularized.The combined treatment has more significant efficacy than alone treatment.Chinese medicine can improve the body immunity，the centralizer thrift and enhance drug curative effect，and reduce the side effects and complications caused by western medicine treatment，which can significantly improve the absorption rate of lesions，promote the sputum bacteria quickly turn.This view has been widely recognized in clinical practice. |
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