| 引用本文:许国猛，施钰琳.“冬病夏治”温阳活血膏治疗心肾阳虚证冠心病心绞痛的疗效和安全性[J].世界中医药,2018,(07):. |
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| “冬病夏治”温阳活血膏治疗心肾阳虚证冠心病心绞痛的疗效和安全性 |
| Comparison on Middle and Long Term Effectiveness of “Dog-days Acupoint Application” Wenyang Huoxue Paste in the Treatment of Coronary Atherosclerotic Heart Disease (Deficiency of Heart and Kidney Yang) |
| 投稿时间：2017-06-01 |
| DOI：10.3969/j.issn.1673-7202.2018.07.014 |
| 中文关键词: 三伏贴穴位贴敷 冠心病心绞痛 心肾阳虚证 临床疗效 |
| English Keywords:Dog-days Acupoint Application Coronary heart disease angina pectoris Heart kidney yang deficiency syndrome Clinical curative effect observation |
| 基金项目:湖北省卫生计生科研计划项目（14HB0521） |
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| 中文摘要: |
| 目的：评价冠心病心绞痛（心肾阳虚证）患者使用三伏贴穴位贴敷疗法的有效性及安全性。方法：选取2015年7月13日至8月21日三伏期间于襄阳市中心医院心内科住院的冠心病心绞痛（心肾阳虚证）患者180例，采用中央随机系统，按照1:1:1比例随机分为普通观察组、贴敷对照组和药物贴敷组，每组60例。普通观察组仅给予常规心绞痛治疗方案进行治疗；贴敷对照组患者在普通观察组的基础上于三伏日进行无药物（淀粉）贴敷；药物贴敷组患者在普通观察组基础上于三伏日进行温阳活血药物贴敷。三伏结束后观察3组患者治疗前后心电图变化，硝酸甘油用量改变、心绞痛症状改变、治疗前后血脂变化评定、患者血浆纤维蛋白原水平、血小板聚集率等指标以及不良反应情况，以及进行有效性和安全性分析。结果：与普通观察组比较，温阳活血膏三伏贴敷疗法能有效提高临床疗效，有效改善患者临床证候和心绞痛症状及心电图改变，同时能有效减少硝酸甘油使用量。结论：三伏贴穴位贴敷对冠心病心绞痛（心肾阳虚证）患者临床疗效确切。 |
| English Summary: |
| To evaluate the effectiveness and safety of “Dog-days Acupoint Application” were applied in patients with coronary heart disease angina pectoris (heart kidney yang deficiency syndrome) clinical curative effect. Methods:A total of 180 cases of coronary heart disease angina pectoris patients with deficiency of heart and kidney yang were randomly divided into general therapy group, acupoint application control group and drug application group, with 60 cases in each group. General treatment group was only given conventional angina treatment; acupoint application control group was given no drugs (starch) application on the basis of general treatment group; drug application group was given Wenyang Huoxue Paste based on the normal control group. The changes of electrocardiogram (ECG), dosage of nitroglycerin and angina symptoms, blood lipid change assessment, plasma fibrinogen concentration, platelet aggregation rate and adverse reactions were observed, and efficacy and safety were analyzed. Results:Compared with normal treatment group, “Dog-days Acupoint Application” Wenyang Huoxue Paste can effectively improve the clinical curative effect, effectively improve the clinical syndrome and angina pectoris and electrocardiogram (ECG) changes, and effectively reduce the nitroglycerin consumption at the same time. Conclusion:“Dog-days Acupoint Application” applied in patients with coronary heart disease angina pectoris (heart kidney yang deficiency syndrome) has certain clinical curative effect. |
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