| 引用本文:吴弘文1，陈岭2，经蕾3，张伟4.自拟益气养阴活血方治疗慢心率多早搏的临床效果[J].世界中医药,2018,(07):. |
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| 自拟益气养阴活血方治疗慢心率多早搏的临床效果 |
| Clinical Observation of Chronic Heart Rate Multiple Premature Beat Treated by Self-made Yiqi Yangyin Huoxue Fang |
| 投稿时间：2017-06-23 |
| DOI：10.3969/j.issn.1673-7202.2018.07.015 |
| 中文关键词: 心律失常 心率 早搏频发 气阴两虚 心脉瘀阻 中医药 |
| English Keywords:Arrhythmia Slow heart rate Frequent premature beat Qi and yin deficiency Heart vessel and blood stasis Traditional Chinese medicine |
| 基金项目:上海市黄浦区科技项目(HKW201547) |
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| 中文摘要: |
| 目的：评价自拟益气养阴活血方治疗气阴两虚，心脉瘀阻型基础心率慢而早搏频发的临床疗效和安全性。方法：选取2015年7月至2017年3月上海市黄浦区东南医院门诊或病房气阴两虚，心脉瘀阻型的基础心率慢而早搏频发的患者60例，随机分为观察组和对照组，每组30例。观察组给予自拟益气养阴活血方治疗，对照组给予丹参片治疗，2组疗程均为3个月。观察2组患者动态心电图，同时对患者心悸、胸闷等症状进行中医症候评分，统计患者治疗过程中心律失常等情况，并对血尿常规，肝肾功能异常等不良反应进行记录以评价安全性。结果：治疗后2组患者心律失常疗效比较，观察组总有效率为63.34%，对照组为33.33%，观察组总有效率显著高于对照组，差异有统计学意义（P<0.05）。治疗后观察组中医症候积分为（11.97±3.73）分，对照组为（15.53±2.10）分，均较治疗前显著降低，且观察组中医症候积分明显低于对照组（P<0.05）。观察组心悸、胸闷、气短乏力、头晕耳鸣、自汗盗汗、午后潮热等中医症状疗效显著高于对照组，数据比较差异有统计学意义（P<0.05）。观察组及对照组治疗后均未出现血常规，肝肾功能异常等不良反应。结论：自拟益气养阴活血方治疗气阴两虚，心脉瘀阻型基础心率慢而早搏频发的心律失常，可改善患者的心律失常程度和症状，安全有效。 |
| English Summary: |
| To evaluate the clinical efficacy and safety of self-made Yiqi Yangyin Huoxue Fang in treating heart qi and yin deficiency and heart vessel and blood stasis syndrome with slow heart beat and frequent premature beat. Methods:Sixty cases of basic heart rate slow and premature beat frequent patients with qi and yin deficiency and heart vessel and blood stasis according to Chinese Medicine syndrome differentiation who were treated in our hospital from July 2017 to March 2017 were randomly divided into treatment group and control group, with 30 cases in each group. The treatment group was given self-made Yiqi Yangyin Huoxue Fang, one dose pre day, twice a day. The control group was treated with Danshen tablets, four tablets each time, three times a day. Course of treatment for two groups was both three months. Dynamic electrocardiogram, traditional Chinese medicine (TCM) syndrome scores, and treatment safety of patients in two groups were observed. Then, the curative effect of arrhythmia and the TCM symptoms after treatment was evaluated. Results:Curative effects on arrhythmia (the total effective rate was 63.34% in treatment group, and 33.33% in control group) in two groups after treatment were significantly different (P<0.05). Treatment group was superior to control group. After treatment, the TCM syndrome scores of the two groups were lower than before treatment, especially in the treatment group (P<0.05). Conclusion:The self-made Yiqi Yangyin Huoxue Fang is safe and effective for the treatment of patients with the qi and yin deficiency and heart vessel and blood stasis syndrome with slow heartbeat and frequent premature beat. |
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