| 引用本文:汪洪波，杨远，宋妮.穴位贴敷治疗类风湿性关节炎湿热痹阻证的疗效[J].世界中医药,2018,(07):. |
|
| 穴位贴敷治疗类风湿性关节炎湿热痹阻证的疗效 |
| Clinical Efficacy Observation on Acupoints Application in the Treatment of Patients with Rheumatoid Arthritis with Dampness-Heat Obstruction Syndrome |
| 投稿时间：2017-09-21 |
| DOI：10.3969/j.issn.1673-7202.2018.07.044 |
| 中文关键词: 中医药 穴位贴敷 辨证论治 论治探讨 分子机制 湿热痹阻证 随机对照研究 类风湿性关节炎 |
| English Keywords:Traditional Chinese medicine Acupoints application Treatment according to syndrome differentiation Discussion on treatment Molecular mechanism Dampness-heat obstruction syndrome Randomized controlled study Rheumatoid arthritis |
| 基金项目:秦皇岛市科学技术局(201602A118） |
|
| 摘要点击次数: 1272 |
| 全文下载次数: 1086 |
| 中文摘要: |
| 目的：探讨穴位贴敷治疗类风湿性关节炎（RA）湿热痹阻证的疗效。方法：选取2016年1月至2017年1月秦皇岛市中医医院收治RA湿热痹阻证患者128例作为研究对象，以数字随机表法分为观察组和对照组，每组64例。2组均给予甲氨蝶呤联合来氟米特治疗，观察组在此基础上给予穴位贴敷治疗。观察2组基线期及治疗后（治疗后12周）各项症状评分、理化指标及晨僵时间的变化，对其疗效有效率和安全性给予评价。结果：观察组治疗有效率显著高于对照组，差异有统计学意义（P<0.05）。2组不良反应发生率基本相同，差异无统计学意义（P>0.05）。治疗期，2组各项症状评分、理化指标及晨僵时间基本相同，差异无统计学意义（P>0.05）。治疗后，观察组关节压痛、关节肿痛、关节活动的评分、红细胞沉降率（ESR）、类风湿因子（RF）、C反应蛋白（CRP）、免疫球蛋白(IgG)的水平及晨僵时间均显著低于对照组，差异有统计学意义（P<0.05）。结论：穴位贴敷治疗RA湿热痹阻证安全有效。 |
| English Summary: |
| To explore the curative effect of acupoints application in the treatment of patients with rheumatoid arthritis (RA) of dampness-heat obstruction syndrome. Methods:A total of 128 patients with RA selected from January 2016 to January 2017 in our Hospital were divided into observation group and control group according to the random indicator method, with 64 cases in each group. Patients of both groups were given Methotrexate Tablets combined with Leflunomide treatment, and acupoints application was added in the observation group．Changes in symptom score, physicochemical indexes and morning stiffness time in the groups were observed baseline phase and 12 week after treatment. The efficacy and safety of the clinical study were evaluated by calculating efficacy index. Results:The total effective rate of the observation group was higher than that of the control group, with statistically significant difference (P<0.05). The rate of adverse reaction of two groups was basically the same and there was no significant difference (P>0.05). Symptom score, physicochemical indexes and morning stiffness times of two groups were basically the same and there was no significant difference after treatment (P>0.05). After treatment, the scores of joint pressure pain, joint swelling and pain, joint activity, ESR, RF, CPR, LgC and morning stiffness were significantly lower than those in the control group, and the difference was statistically significant (P<0.05). Conclusion:Acupoints application treatment to RA of dampness-heat obstruction syndrome is safe and effective, and it is worthy of clinical application. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
