Sepsis resulted from a host's systemic inflammatory response syndrome (SIRS) to infection, with the deterioration of the disease it will develop into severe sepsis, septic shock, multiple organ dysfunction and other serious consequences. Sepsis acute renal injury is familiar, and the occurrence of acute renal injury sepsis exists a variety of complex mechanisms. Nowadays, acute renal injury for sepsis has not achieved effective treatment yet, and the actively looking for Chinese and western medicine treatment of sepsis kidney injury method is particularly urgent. Chinese medicine single and compound treatment of sepsis have made some progress, to be further combined with modern medicine to deal with challenge of acute renal injury sepsis.