| 引用本文:徐榛敏1，刘雪梅2，曾子修2，张昕洋2，刘晓汉2，张允岭3.中医药对缺血性卒中后神经血管单元的保护作用[J].世界中医药,2018,(08):. |
|
| 中医药对缺血性卒中后神经血管单元的保护作用 |
| Progress of Study on Traditional Chinese Medicine in Protecting Neuro Vascular Unit after Ischemic Stroke |
| 投稿时间：2018-04-08 |
| DOI：10.3969/j.issn.1673-7202.2018.08.062 |
| 中文关键词: 缺血性卒中 神经血管单元 中医药 保护作用 |
| English Keywords:Ischemic stroke Neuro vascular unit Traditional Chinese medicine Protection effect |
| 基金项目:国家自然科学基金资助项目（81774250)；北京市自然科学基金资助项目（7182099)；北京中医药大学基本科研业务费自主选题项目（2018-JYB-XSCXCY01) |
|
| 摘要点击次数: 1061 |
| 全文下载次数: 1003 |
| 中文摘要: |
| 神经血管单元(Neurovascular Unit，NVU)的提出改变了单纯恢复脑组织血供是治疗卒中后神经元损伤的关键这一观点，使人们认识到缺血性卒中诱导的脑损伤是一个复杂的病理过程，涉及到NVU中的各组成成分，而神经保护的目标应从之前传统观点中对单一的神经元保护扩展为对多组成成分的全面保护，药物保护的靶点也应该针对各种有害因子。真正认识到全面保护会使缺血性卒中的治疗达到更理想的效果。中药具有多组分、多靶点、多环节、多途径的全面保护及整体调节的优势和特点，与神经血管单元治疗策略的要求相吻合。现主要基于神经血管单元，对中医药治疗不同病机的中风研究进展进行综述，以期为后续中医药治疗缺血性卒中的临床研究及方案选取提供一定参考。 |
| English Summary: |
| The proposal of neurovascular unit(NVU)has changed the idea that pure rehabilitation of brain blood supply is the key to the treatment of neuron damage after a stroke which makes people realize that the brain injury induced by ischemic stroke is a complex pathological process.It involves the various components of NVU,and nerve protection goals should expand into a comprehensive protection of multiple components from a single neuron protection.Drug protection should target at all kinds of harmful factors in pathological process.The identification of comprehensive protection would allow the treatment of ischemic stroke to achieve ideal effects.The traditional Chinese medicine has the advantages and characteristics of multi-component,multi-target,multi-link and multi-channel protection and overall regulation,which is in line with the requirements of the treatment strategy of neurovascular unit.Based on neural vascular unit,this paper reviewed the research progress of traditional Chinese medicine treatment of ischemic stroke in order to provide certain reference for follow-up treatment of traditional Chinese medicine clinical research and treatment of ischemic stroke. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
