Abstract:To investigate the effects of adjuvant therapy with modified Sanzi Yangqin Decoction on lung function and airway remodeling in patients with bronchial asthma.Methods:A total of 78 patients with bronchial asthma admitted to Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical University from January 2016 to June 2017 were selected and randomly divided into observation group and control group,with 39 cases in each group.Both groups received conventional symptomatic supportive treatment after admission.The observation group was treated with modified Sanzi Yangqin Decoction at the same time,and both groups were continuously treated for 10 days.The clinical efficacy and the changes of Traditional Chinese Medicine (TCM) syndrome score of both groups before and after treatment were compared,and the changes of lung function and airway remodeling in both groups were detected and compared,and the adverse reactions were observed during the treatment period.Results:The total effective rate of observation group (89.74%) was higher than that of control group (71.79%) (P<0.05).The recurrence rate of observation group was lower than that of control group after 6 months discharge (P<0.01).After the treatment,the scores of nasal obstruction,cough,itchy throat,shortness of breath in both groups were decreased (P<0.01),and the above indexes of observation group decreased more than those of control group (P<0.05 or P<0.01).The FEV1 and MVV of both groups were increased after treatment,and the scores of observation group increased more than those of control group (P<0.05 or P<0.01).The FEF75%,Wai,Wam,Wat were decreased compared with before the treatment,and the scores in observation group decreased more than those of control group (P<0.05 or P<0.01).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion:The combination of modified Sanzi Yangqin Decoction and conventional medicine in the treatment of bronchial asthma can effectively relieve the clinical symptoms,inhibit the happening and progress of airway remodeling and improve the pulmonary function of the patients.It has low recurrence rate,and the near and long term effects are significant.