Ningxia wolfberry plant, as the only raw medicinal herbs of Chinese wolfberry, is included in the Pharmacopoeia of People's Republic of China, which is mainly distributed in the northern part of China, such as Ningxia, Gansu, Qinghai, Inner Mongolia, Xinjiang and other places.It is one of the commonly used medicinal materials.Due to the large demand, wild wolfberry has long been in short supply.Now most wolfberry is introduced and cultivated.However, due to many differences in ecological environment and geographical conditions, the quality of wolfberry is uneven, and the quality of market circulation is chaotic.On the basis of the literature research, the fourth survey of traditional Chinese medicine resources and dynamic monitoring data, this paper screened the range of six factors of the latitude and longitude, altitude, annual mean temperature, annual precipitation, soil type, slope and sunshine time of Ningxia wolfberry distribution area, and under the assistance of the remote sensing and GIS technology, with validation of data in the field investigation, ultimately determined the suitable distribution area of Ningxia wolfberry.