To explore the composing principles of prescriptions for hashimoto thyroiditis (HT) by using traditional Chinese medicine (TCM) Inheritance System. Methods:The literature on TCM prescriptions for HT in CNKI were collected, then the data were entered into the TCM inheritance system, which was used to analyze the composing principles of the prescriptions for HT. Results:The syndrome distribution rules and composing principles were screened based on the analysis of 232 prescriptions by using TCM inheritance system. The frequency of herbs was analyzed. Twenty-two core combinations and eleven new prescriptions were explored form the database. Conclusion:The complex composing rules of the prescriptions for HT collected in CNKI have been clarified by TCM inheritance system. The TCM inheritance system provides a reference for the clinical treatment of TCM and development for HT.