| 引用本文:李新芝，薛欣欣.益气活血解毒方对冠脉支架植入术后心脏康复的治疗效果及炎性反应介质的干预[J].世界中医药,2018,(10):. |
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| 益气活血解毒方对冠脉支架植入术后心脏康复的治疗效果及炎性反应介质的干预 |
| Effects of Yiqi Huoxue Jiedu Decoction on Cardiac Rehabilitation After Coronary Stent Implantation and Its Influence on Inflammatory Factors |
| 投稿时间：2018-07-07 |
| DOI：10.3969/j.issn.1673-7202.2018.10.011 |
| 中文关键词: 益气活血解毒方 冠脉支架植入术 白细胞介素-6 高敏C反应蛋白 症状积分 左心室射血分数 6 min步行距离 疗效 |
| English Keywords:Yiqi Huoxue Jiedu Decoction Coronary stenting Interleukin-6 High sensitivity C reactive protein Symptom score Left ventricular ejection fraction 6 min walking distance Curative effect |
| 基金项目:北京市自然科学基金项目（7151004） |
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| 中文摘要: |
| 目的：探讨益气活血解毒方对冠脉支架植入术后心脏康复的治疗效果及炎性反应介质的干预作用。方法：选取2016年8月至2017年9月首都医科大学附属北京朝阳医院收治的行冠脉支架植入术后心脏康复患者82例，回顾性分析其临床资料，根据术后治疗措施不同分为对照组和观察组，每组41例。对照组仅给予常规西药治疗，观察组在对照组治疗的基础上联合益气活血解毒方治疗。2组患者均连续治疗6个月。比较2组患者临床疗效；统计2组患者临床症状评分；检测并比较2组患者治疗前和治疗6个月后炎性反应介质水平、心功能变化。结果：观察组总有效率为92.68%，显著高于对照组的75.61%（P<0.05）。与治疗前比较，治疗6个月后2组患者心悸、痰多、胸闷气短及神倦乏力等临床症状积分明显下降，差异有统计学意义（P<0.05），且观察组比对照组下降明显，差异有统计学意义（P<0.05）。治疗后，2组患者高敏C反应蛋白（hs-CRP）、白细胞介素-6（IL-6）水平与治疗前比较均明显下降，差异有统计学意义（P<0.05），且观察组比对照组下降明显，差异有统计学意义（P<0.05）。治疗6个月后，2组患者左心室射血分数（LVEF）、6 min步行距离与治疗前比较均明显升高，差异有统计学意义（P<0.05），且观察组比对照组升高明显，差异有统计学意义（P<0.05）。结论：对行冠脉支架植入术后心脏康复患者在常规治疗基础上联合益气活血解毒方可有效改善其临床症状，减轻炎性反应，对其术后效果和心功能的提高具有重要作用。 |
| English Summary: |
| To explore the effects of Yiqi Huoxue Jiedu Decoction on cardiac rehabilitation after coronary stent implantation and its influence on inflammatory factors.Methods:A total of 82 patients undergoing cardiac rehabilitation after coronary stent implantation were hospitalized in Beijing Chaoyang Hospital from August 2016 to September 2017 were selected.A retrospective analysis of the clinical data showed that,according to the difference of postoperative treatment,they were divided into observation group and control group with 41 cases in each group.The control group was only given conventional western medicine,while the observation group was combined with Yiqi Huoxue Jiedu Decoction on the basis of control group.Two groups of patients were treated continuously for 6 months.The clinical efficacy of the two groups were compared,and the clinical symptom scores of the two groups were counted.In addition,the levels of inflammatory factors and cardiac function were compared between the two groups before and 6 months after treatment.Results:The total effective rate of the observation group was 92.68%,which was significantly higher than 75.61% of the control group (P<0.05).After 6 months of treatment,the two groups of patients with palpitations,sputum,chest tightness and fatigue and fatigue were significantly lower than before treatment (P<0.01),and the data of observation group was significantly lower than the data of control group (P<0.01).After treatment,the levels of hs-CRP and IL-6 in two groups were significantly lower than those before treatment (P<0.01),and the observation group was significantly lower than that in the control group (P<0.01).After 6 months of treatment,the LVEF and walking distance of 6 min in the two groups were significantly higher than before the treatment (P<0.01),and the study group was significantly higher than the control group (P<0.01).Conclusion:The Yiqi Huoxue Jiedu Dcoction on the basis of conventional treatment after coronary stent implantation can effectively relieve the clinical symptoms and alleviate the inflammatory reaction,which have an important effect on the improvement of the cardiac function of the postoperative. |
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