| 引用本文:王洪霞，胡金霞.复方丹参滴丸联合阿托伐他汀治疗冠心病合并血脂代谢异常老年患者的疗效[J].世界中医药,2018,(10):. |
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| 复方丹参滴丸联合阿托伐他汀治疗冠心病合并血脂代谢异常老年患者的疗效 |
| Efficacy Analysis of Compound Danshen Dripping Pills and Atorvastatin in Elderly Patients with Coronary Heart Disease Complicated with Abnormal Blood Lipid Metabolism |
| 投稿时间：2017-06-27 |
| DOI：10.3969/j.issn.1673-7202.2018.10.016 |
| 中文关键词: 冠心病:血脂代谢异常 中西医结合疗法 复方丹参丸 阿托伐他汀 临床疗效 |
| English Keywords:Coronary heart disease with abnormal lipid metabolism Integrated traditional Chinese and Western medicine Compound Danshen pill Atorvastatin Clinical effect |
| 基金项目:新疆维吾尔自治区自然科学基金课题（2015211C152） |
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| 中文摘要: |
| 目的：探讨复方丹参滴丸联合阿托伐他汀治疗冠心病合并血脂代谢异常老年患者的疗效。方法：选取2013年1月至2016年6月新疆维吾尔自治区中医医院老年病科收治的冠心病合并血脂代谢异常老年患者98例为研究对象，随机分为观察组和对照组，每组49例。对照组患者给予阿托伐他汀治疗，观察组患者给予复方丹参滴丸联合阿托伐他汀治疗，治疗结束后对2组临床疗效进行评价，并比较治疗前后2组患者心功能指标、血脂水平、炎性因子水平及血液流变学相关指标。结果：观察组总有效率为91.84%，对照组总有效率为79.59%，2组总有效率比较，差异有统计学意义（P<0.05）；治疗前，2组患者的心功能指标、血脂水平、炎性反应因子水平及血液流变学指标比较，差异无统计学意义（P>0.05）,治疗后观察组心功能指标（CI、CO、LVEF、LVEDD）、血脂水平（TG、TC、HDL-C、HDL-C）、炎性因子（CRP、TNF-α、IL-6）水平、血液流变学指标（血红蛋白、血浆黏度、纤维蛋白原）改善程度优于对照组（P<0.05）。结论：复方丹参丸联合阿托伐他汀治疗冠心病合并血脂代谢异常老年患者的疗效显著，能够有效改善患者心功能、血脂、炎性因子水平及血液流变学，值得临床推广。 |
| English Summary: |
| To investigate the effect of Compound Danshen dripping pills combined with atorvastatin in elderly patients with coronary heart disease complicated with abnormal blood lipid metabolism. Methods:A total of 98 cases of elderly patients with coronary heart disease complicated with abnormal blood lipid metabolism who were admitted in our hospital from January 2013 to June 2016 were randomly divided into treatment group and control group, with 49 cases in each group. The control group was given atorvastatin treatment, and the treatment group was treated with compound Danshen dripping pills combined with atorvastatin treatment. After treatment, the clinical efficacy of the two groups was evaluated, and the heart function index, index level and inflammatory factors in blood lipids of two groups before and after treatment were compared. Results:The total effective rate of treatment group was 91.84%, and 79.59% in the control group. There was a significant difference between groups (P<0.05). The improvement of heart function index (CI, CO, LVEF treatment, LVEDD), blood lipids (TG, TC, HDL-C, HDL-C), the level of inflammatory factors (CRP, alpha TNF-IL-6) of treatment group was better than the control group. Conclusion:Compound Danshen Pill combined with atorvastatin has a significant efficacy in treating elderly patients with coronary heart disease complicated with abnormal blood lipid metabolism, which can effectively improve cardiac function, blood lipids and inflammatory factors. It is worthy of clinical Guangzhou. |
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