| 引用本文:刘超1，王中琳2.小柴胡汤对中风后眩晕的疗效及机制研究[J].世界中医药,2018,(10):. |
|
| 小柴胡汤对中风后眩晕的疗效及机制研究 |
| Effects and Mechanism of Xiaochaihu Decoction on Vertigo after Stroke |
| 投稿时间：2018-04-17 |
| DOI：10.3969/j.issn.1673-7202.2018.10.027 |
| 中文关键词: 中风 眩晕 小柴胡汤加减 运动功能 日常生活能力 焦虑抑郁状态 血液流变学 临床疗效 |
| English Keywords:Stroke Vertigo Xiaochaihu Decoction Exercise function Activities of daily living Anxiety and depression Hemorheology Curative effect |
| 基金项目:山东省2015年度中医药科技发展计划项目(2015-018) |
|
| 摘要点击次数: 721 |
| 全文下载次数: 586 |
| 中文摘要: |
| 目的:观察小柴胡汤治疗中风后眩晕的疗效,并初步探讨其作用机制。方法:选取2016年1月至2018年1月山东中医药大学第一临床医学院收治的中风后眩晕患者90例,按照随机数字表法随机分为对照组和观察组,每组45例,对照组予氟桂利嗪口服,静脉注射舒血宁注射液,观察组在上述治疗基础上加用小柴胡汤加减,1剂/d,200 mL煎服,早晚温服分服。2组均连续治疗10 d,比较2组治疗前后临床神经功能缺损程度评分量表(NDS)、Fugl-Meyer评分、日常生活能力(ADL)评分、Berg平衡量表评分(BBS)以及血液流变学指标的变化。结果:1)治疗前2组患者NDS评分、FCA评分、Fugl-Meyer评分以及ADL评分差异无统计学意义(P>0.05),经过10 d治疗后2组患者NDS评分下降,FCA评分、Fugl-Meyer评分以及ADL评分均提高,与治疗前比较，差异有统计学意义(P<0.05),观察组优于对照组;2)治疗前2组患者BBS评分、MSQ、HAMA、HAMD评分差异无统计学意义(P>0.05),经过10 d治疗后2组患者BBS评分升高,MSQ、HAMA、HAMD评分均下降,与治疗前比较，差异有统计学意义(P<0.05),观察组优于对照组;3)治疗前2组患者PV、FIB及WBV水平差异无统计学意义(P>0.05),经过10 d治疗后2组患者PV、FIB及WBV水平均降低,与治疗前比较，差异有统计学意义(P<0.05),观察组优于对照组;4)观察组临床总有效率为97.78%,与对照组70%比较，差异有统计学意义(P<0.05,χ2=2.88)。结论:小柴胡汤加减对中风后眩晕有理想疗效,可能通过改善血液流变学实现治疗作用。 |
| English Summary: |
| To observe the effects of Xiaochaihu Decoction on vertigo after stroke,and to analyze its mechanism.Methods:A total of 90 patients with post-stroke vertigo admitted to the First Clinical Medical College of Shandong University of Traditional Chinese Medicine from January 2015 to September 2016 were randomly divided into the control group and the observation group according to the random number table method,with 45 cases in each group.The control group was given flunarizine orally and Shuxuening Injection intravenously.The observation group was given Xiaochaihu Decoction on the basis of the above treatment,with 1 dose per day,and 200 mL decoction was taken in the morning and evening.The two groups were treated for 10 d continuously,and the changes of clinical nerve function defect scale (NDS),Fugl-Meyer score,daily living ability (ADL) score,Berg balance scale score (BBS) and hemorheological indexes were compared before and after treatment in the two groups.Results:1) There was no significant difference in NDS score,FCA score,Fugl-Meyer score and ADL score before treatment (P>0.05).After 10 days' treatment,the NDS scores of the two groups were decreased,and FCA score,Fugl-Meyer score and ADL score were all improved.The difference was statistically significant compared with those before the treatment (P<0.05).The observation group was superior to the control group; 2) there was no significant difference in BBS score,MSQ,HAMA and HAMD score in the two groups of patients before treatment (P>0.05).After 10 days' treatment,the BBS scores in two groups were increased.MSQ,HAMA and HAMD scores were all decreased,and the difference was statistically significant compared with those before the treatment (P<0.05).The observation group was superior to the control group; 3) there was no significant difference in the levels of PV,FIB and WBV in the two groups before treatment (P>0.05).After 10 days' treatment,the levels of PV,FIB and WBV decreased in two groups,and the difference was statistically significant compared with that before treatment (P<0.05).The observation group was superior to the control group; 4) the total effective rate was 97.78% in the observation group,which was significantly different from 70% in the control group (P<0.05,χ2=2.88).Conclusion:Xiaochaihu Decoction has an ideal effect on vertigo after stroke,and it may achieve therapeutic effect by improving hemorheology. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
