To observe and analyze the effects of Jingui Shenqi Pill on endocrine metabolism in polycystic ovary syndrome.Methods:A total of 112 cases with polycystic ovary syndrome who were admitted in our hospital from May 2013 to December 2016 were selected by using the random number table and were randomly divided into control group and observation group, with 56 cases in each group.The control group was treated with Ethinylestradiol and Cyproterone Acetate Tablets, and the observation group was added Jingui Shenqi Pill.Endocrine and hormone levels of two groups were observed before treatment, after treatment and 3 months after treatment.The hair, menstruation and ovaries were observed.And all data were statically analyzed.Results:(1) After treatment, the LH of the two groups decreased and FSH increased (P<0.05).The observation group was better than the control group (P<0.05), and there was no statistically significant difference between the observation group and the treatment group (P>0.05).(2) F-G score, ovarian volume of two groups decreased significantly after treatment.The proportion of normal menstrual was significantly increased, and acne decreased.The observation group was better than the control group (P<0.05), while the difference was not statistically significant in the observation group after treatment and follow-up (P>0.05).(3) After treatment, T and PRL decreased significantly (P<0.05).The observation group were significantly better than the control group after treatment and follow-up (P<0.05).There were no statistically significant difference in the observation group in 3 months of follow-up and after treatment (P>0.05).Conclusion:Jingui Shenqi pill in treatment of polycystic ovary syndrome can effectively correct the endocrine and metabolic hormone levels in patients, improve menstruation and ovulation, with more stable the long-term effects.