| 引用本文:曹青青，杨丽丽，李文林，徐勰，卞尧尧，连紫宇，田梦菲，陈涤平.易筋经防治老年人原发性骨质疏松的Meta分析[J].世界中医药,2018,(10):. |
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| 易筋经防治老年人原发性骨质疏松的Meta分析 |
| Meta-analysis of Muscle-bone Strengthening Exercise in the Prevention and Treatment of Elderly Primary Osteoporosis |
| 投稿时间：2017-03-12 |
| DOI：10.3969/j.issn.1673-7202.2018.10.067 |
| 中文关键词: 健身气功 易筋经 原发性骨质疏松 骨密度 临床疗效 随机对照试验 系统评价 Meta分析 |
| English Keywords:Health Qigong Muscle-bone strengthening exercise Primary osteoporosis Bone mineral density Clinical effect Randomized controlled trials Systematic review Meta-analysis |
| 基金项目:国家中医药管理局2015度国家中医临床研究基地业务建设科研建设专项课题（JDZX2015127）；江苏省研究生科研创新计划项目（KYCX17_1313） |
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| 中文摘要: |
| 目的:评价易筋经防治老年人原发性骨质疏松的疗效。方法：应用计算机检索中国知网、万方医学数据库、Web of Science、The Cochrane Library、EMbase、PubMed、VIP和CBM，样本量文种不限，收入易筋经防治老年人原发性骨质疏松的临床随机对照试验（RCT）。根据Cochrane handbook5.1.0评价研究质量，应用RevMan5.3和Stata11.0软件进行Meta分析。结果：共纳入3个RCTs，185名受试者，易筋经在增加患者腰椎骨密度和股骨颈骨密度方面差异有统计学意义（MD=0.54，95%CI[0.24，0.83]，P=0.0004，MD=0.11，95%CI[0.07，0.15],P<0.00001），缓解患者骨痛症状差异有统计学意义（MD=-0.82，95%CI[-1.09，-0.55],P<0.00001，MD=-1.65，95%CI[-1.99，-1.31],P<0.00001）。结论：易筋经对老年人原发性骨质疏松的防治有一定的疗效，但由于纳入的研究较少、质量不高。 |
| English Summary: |
| To assess the effect of muscle-bone strengthening exercise for elderly primary osteoporosis by using meta-analysis.Methods:We searched CNKI,WanFang Data,Web of Science,The Cochrane Library,EMbase,PubMed,VIP and CBM,irrespective of language restrictions.The samples included randomized controlled trials(RCTs)regarding muscle-bone strengthening exercise for elderly osteoporosis.The quality was evaluated and studied by Cochrane handbook 5.1.0 and analyzed by RevMan 5.3 and Stata 11.0 software.Results:3 RCTs involving 185 subjects were included.Meta-analysis showed that muscle-bone strengthening exercise was statistically significant in improvement on bone mineral density(BMD)and femur neck BMD(FMBMD)(MD=0.54，95% CI [0.24，0.83],P=0.0004,MD=0.11，95% CI [0.07,0.15],P<0.00001).Additionally,muscle-bone strengthening exercise was statistically significant in relieving bone pain(MD=-0.82,95%CI [-1.09,-0.55],P<0.00001,MD=-1.65,95%CI[-1.99,-1.31],P<0.00001).However,problem on the data biochemical criterion of bone metabolism was doubted.Thus,data was not analyzed.Conclusion:Muscle-bone strengthening exercise has some effects on prevention and treatment of elderly primary osteoporosis.But we must be careful to that result due to few studies included and poor quality. |
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