| 引用本文:王羽侬1，林欢儿2，蔡玲玲3，张丰川3，李流云4，张雪4，郭丽媛4，王莹4，王家悦4.黄褐斑的中医体质类型与皮损分布及严重程度相关性的临床研究[J].世界中医药,2018,(11):. |
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| 黄褐斑的中医体质类型与皮损分布及严重程度相关性的临床研究 |
| Clinical Study on Relationship between Type of Traditional Chinese Medicine Constitution and Distribution and Severity of Skin Lesions in Melasma |
| 投稿时间：2018-10-10 |
| DOI：10.3969/j.issn.1673-7202.2018.11.004 |
| 中文关键词: 黄褐斑 中医体质 皮损特征 |
| English Keywords:Melasma Traditional Chinese medicine constitution Lesion characteristics |
| 基金项目:北京中医药大学自主选题在读研究生项目(2015-JYB-XS167)——黄褐斑面部皮损分型与中医证候要素相关性研究;北京中医药大学青年教师专项课题(2013-QNJSZX015)——美容白玉膏外用治疗黄褐斑的临床疗效研究;北京中医药大学教育科研课题(XJY17001)——中医皮肤病辨病与辨证结合的数据库建立与新型教学软件研发;北京中医药大学横向科研项目(HX201706)——复方紫草油治疗慢性湿疹(血虚风燥证)的临床及动物实验研究 |
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| 中文摘要: |
| 目的:探讨黄褐斑患者中医体质与面部皮损分布及严重程度的相关性。方法:选取2016年1月至2017年12月北京中医药大学东方医院皮肤科门诊收治的黄褐斑患者246例,分析其中医体质类型与皮损分布及严重程度的相关性。结果:不同体质类型的黄褐斑患者间,其MASI总分分段情况类型差异有统计学意义(P<0.05):0~10分中,阳虚质所占比例最多;10~20中,气郁质所占比例最多;20~30分及30~40分中,血瘀质所占比例最多。不同体质类型间前额及颏部MASI评分的差异无统计学意义,而左颧、右颧部评分的差异有统计学意义。不同体质类型的MASI总分与不同部位MASI分数存在一定相关性,阳虚质、阴虚质、痰湿质、平和质患者的MASI总分与右颧部的MASI分数相关性最大,血瘀质、气郁质、湿热质、气虚质患者的MASI总分与左颧部的MASI分数相关性最大。未发现黄褐斑患者MASI总分与上颌部及颏部MASI评分相关的要素。结论:黄褐斑患者中医体质分型与皮损发生部位及严重程度评分存在一定的相关性,但仍需要大样本研究及更先进的技术进一步验证不同体质类型对黄褐斑皮损生理特征的影响。 |
| English Summary: |
| To explore the correlation between traditional Chinese medicine (TCM) syndrome type and skin lesions site as well as the severity score of melasma.Methods:A total of 246 patients with melasma treated at Dongfang Hospital of Beijing University of Chinese Medicine from January 2016 to December 2017 were selected to analyze the correlation between TCM syndrome type and skin lesions site as well as the severity score of melasma.Results:Between the melasma patients with different TCM constitution types，the total MASI score segmentation was significantly different.Yang deficiency accounted for the largest proportion in 0-10 points.Constitution of qi stasis accounted for the largest proportion in 10-20 points.Blood stasis constitution accounted for the largest proportion in 20-30 and 30-40 points.There was no significant difference in MASI scores of forehead and chin among different types of constitution，while there were significant differences in left zygomatic and right zygomatic scores.There were correlated relationship between the total MASI scores and MASI scores in different parts of different types of constitutions.MASI scores of patients of yang deficiency constitution，yin deficiency constitution，phlegm-dampness constitution and harmonious constitution had the highest correlation with MASI scores of right zygomatic.The MASI scores of blood stasis constitutions，qi stagnation constitution，damp-heat constitution and qi deficiency constitution had the highest correlation with MASI score of left zygomatic.There was no evidence of total MASI score associating with MASI scores in maxillary and chin among patients with melasma.Conclusion:There is a certain statistical correlation between the TCM constitution of melasma patients and skin lesions site as well as the severity score.A large sample studies and more advanced technology are still needed to test and verify the effects of different types of constitutions on the physiological characteristics of melasma. |
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