世界中医药

目的:探究生脉益血汤联合冠心舒通胶囊治疗冠心病心绞痛的疗效。方法:选取2016年1月至2016年10月商洛市中心医院收治的冠心病心绞痛患者85例,按照随机数字表法随机分为对照组(n＝42)和观察组(n＝43);对照组患者采用冠心舒通胶囊进行治疗,观察组患者在对照组患者治疗的基础上增加生脉益血汤进行联合治疗,坚持服药8周;治疗8周后,观察比较2组患者的疗效、心电图疗效、心绞痛发作次数及持续时间、硝酸甘油日耗量、不良反应数据。结果:治疗8周后,观察组和对照组患者的总有效率分别为93.02%、78.57%,观察组高于对照组(P<0.05);观察组和对照组患者的心电图疗效总有效率分别为86.05%、66.67%,观察组高于对照组(P<0.05);观察组患者心绞痛发作频率,持续时间,硝酸甘油的消耗下降的幅度高于对照组(P<0.05);观察组与对照组患者在治疗过程的不良反应的总发生率分别为4.65%、7.14%,2组数据差异无统计学意义。结论:生脉益血汤联合冠心舒通胶囊能够减少心绞痛发作频率、持续时间及硝酸甘油平均日耗量,治疗冠心病心绞痛疗效显著,安全性较高,具有重要的临床推广价值。

English Summary:

To study the curative effect of Shengmai Yixue Decoction combined with Guanxin Shutong Capsule in the treatment of coronary heart disease and angina pectoris.Methods:A total of 85 patients with angina pectoris of coronary heart disease during the period were selected in Shangluo City Central Hospital from January 2016 to October 2016，and they were divided into control group and observation group by the random number method.The control group was treated with Guanxin Shutong Capsule for treatment; patients in the observation group added combined therapy of Shengmai Yixue Decoction on the basis of the control group; The medication last for 8 weeks.After 8 weeks of treatment，the curative effect，the efficacy of (Electrocardiograph) ECG，the number and duration of angina pectoris，the daily consumption of nitroglycerin and the adverse reaction data of two groups were observed and compared.Results:After 8 weeks of treatment，the total effective rate of the control group and the observation group were respectively 93.02% and 78.57%，and the observation group was higher than those of the control group (P<0.05).The total effective rates of ECG in the observation group and the control group were 86.05% and 66.67%，and the observation group was higher than the control group (P<0.05).The frequency，duration and consumption of nitroglycerin decreased more in the observation group than in the control group (P<0.05).The total incidence rate of adverse reactions in the treatment process of the observation group and control group were 4.65% and 7.14%，and there was no significant difference between the data of the two groups.Conclusion:Shengmai Yixue Decoction combined with Guanxin Shutong Capsule can reduce the frequency and duration of angina pectoris and the average daily consumption of nitroglycerin.The curative effect in treatment of angina pectoris is significant，with high safety and important clinical value.

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