| 引用本文:曾祖平1，石佳2，王子君3，王宏1.紫草乳膏提取工艺研究[J].世界中医药,2018,(11):. |
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| 紫草乳膏提取工艺研究 |
| Study on the Extraction Process of Zicao Cream |
| 投稿时间：2017-08-24 |
| DOI：10.3969/j.issn.1673-7202.2018.11.051 |
| 中文关键词: 紫草乳膏 提取工艺 羟基萘醌总色素 分光光度法 羟基红花黄素A 高效液相色谱法 正交试验 含量测定 |
| English Keywords:Zicao cream Extraction process Total pigment of hydroxynaphthalene Spectrophotometry Hydroxysafflor yellow A HPLC Orthogonal test Content determination |
| 基金项目:北京中医药科技发展资金项目（JJ2016-03） |
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| 中文摘要: |
| 目的：探讨紫草乳膏中药材提取工艺的优选方法。方法：采用分光光度法测定羟基萘醌总色素含量，采用高效液相色谱法(HPLC)测定羟基红花黄素A含量，以此作为评价指标，进行正交试验，优选药材提取工艺。结果：紫草、白芷的提取工艺为饮片粗粉加乙醇4倍量浸渍48 h后开始渗漉，溶剂用量为10倍；红花、当归的提取工艺为饮片用水浸泡0.5 h后，70 ℃温浸2次，60 min/次，第1次用水12倍量，第2次用水10倍量。结论：紫草乳膏提取工艺合理可行，为紫草乳膏的成型工艺研究及质量控制奠定基础。 |
| English Summary: |
| To optimize the extraction process of Zicao cream. Methods:The contents of total pigment of hydroxynaphthalene were determined by spectrophotometry, and hydroxysafflor yellow A was determined by HPLC. The contents of total pigment of hydroxynaphthalene and hydroxysafflor yellow A were used as the indices for evaluation. Orthogonal test was applied to optimize the extraction process. Results:The extraction process of Arnebiae Radix and Angelicae Dahuricae Radix were found to be soaked with 95% alcohol for 48 h using coarse powders, and then percolated with 10 times amount of 95% alcohol; The extraction process of Carthami Flos and Angelicae Sinensis Radix were found to be soaked with water for 30 min,and then extracted by warm maceration at 70 ℃ with 12 times amount of water at the first time and 10 times amount of water at the second time, 60 min each time. Conclusion:The process is reasonable and feasible, and lays a foundation for the formation technology of Zicao cream and its quality standards. |
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