引用本文:梁巧静1,梁维萍2,3,李琼1,郭宏伟1,2,朱丹1.土茯苓抗痛风作用研究进展[J].世界中医药,2018,(11):. |
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土茯苓抗痛风作用研究进展 |
Research Progress of the Anti-gout Effects of Glabrous Greenbrier Rhizome |
投稿时间:2017-10-29 |
DOI:10.3969/j.issn.1673-7202.2018.11.063 |
中文关键词: 土茯苓 痛风 高尿酸血症 痛风性关节炎 高尿酸血症肾病 化学成分 作用机制 研究进展 |
English Keywords:Glabrous Greenbrier Rhizome Gout Hyperuricemia Gout arthritis Hyperuricemic nephropathy Chemical component Mechanism Research progress |
基金项目:广西科学研究与技术开发计划项目(桂科攻1598013-8)——壮药配方雷公降压颗粒的研制 |
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中文摘要: |
随着痛风发病率的逐年升高,痛风疾病的难愈性和反复发作性已成为当前临床治疗的主要问题和难点。目前使用的抗痛风西药降低尿酸和控制炎性反应在短期内疗效肯定,但长期应用会导致诸多不良反应。土茯苓作为一种传统中药,临床上可用于治疗痛风,其效果显著且不良反应少。本文将土茯苓主要化学成分以及治疗痛风作用的机制作一综述,为将其研究开发成为抗痛风药物提供参考。 |
English Summary: |
As the morbidity rate of gout increase significantly year by year,the refractory and the recurrent nature of gout has become the main problems and difficulty in clinical treatment.Currently,the application of anti-gout western medicine results effectively in inflammation controlling and uric acid reduction.However,the long-term application might lead to many adverse reactions.Glabrous Greenbrier Rhizome,as a kind of common traditional Chinese medicine,has remarkable effects in clinical treatment of gout,with little side effects.This paper reviewed some progresses on chemical constituents and anti-gout mechanism of Glabrous Greenbrier Rhizome,aiming at providing references for its research and development into anti-gout drugs. |
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