Due to the lack of systematic and scientific planting technical norms for a long period of time in Yunnan Paris polyphylla production areas,the low level of standardized production,serious diseases and insect pests,and abuse of chemical fertilizers and pesticides are widespread,which seriously restricts the sustainable utilization of Yunnan Paris polyphylla and the development of regional economy.The key to solve this problem is to carry out pollution-free cultivation in Yunnan Paris polyphylla.This study aims at discussing the pollution-free cultivation techniques of Yunnan Paris polyphylla,including the site selection of GMPGIS-II guidance base,field management,integrated pest and disease control techniques,etc.This system can provide reference for pollution-free fine cultivation of Yunnan Paris polyphylla.