To explore the effects of traditional Chinese medicine on the index of pancreatic microcirculation in patients with severe pancreatitis.Methods:A total of 63 cases of severe pancreatitis diagnosed in Zhongshan Nanlang Hospital from January 2015 to May 2017 were selected as the research object.According to the random number table method,all patients were divided into control group (n＝31) and observation group (n＝32).The control group were treated with gastrointestinal decompression,anti-infection,correction of electrolyte balance,pain relief and other conventional treatment with somatostatin injection treatment,while observation group were given modified Chailing Chengqi Decoction on the basis of the control group.Then the clinical curative effect and the changes of pancreatic microcirculation index of two groups were compared.Results:The clinical effective rate in observation group was significantly higher than that in control group (P<0.05).In observation group,the patients' recovery time who had abdominal pain,hyperthermia and bowel sounds and the hospitalized period was shorter than those in the control group (P>0.05).After treatment,the pancreatic blood flow in observation group was higher than that in control group (P<0.05),and the plasma viscosity in observation group was lower than that in control group (P<0.05).The levels of TXB2,GMP-140 and ET-1 in the observation group were lower than those in control group (P<0.05),and the serum NO levels were higher than those in control group (P<0.05).Conclusion:The modified decoction based on Chailing Chengqi Decoction on the treatment of traditional Chinese medicine prescription combined with conventional therapy can effectively improve the patients with severe acute pancreatitis of pancreatic microcirculation.