| 引用本文:周晓曦，陈谋，黄林.益气健脾和胃法治疗脾胃虚弱型慢性萎缩性胃炎患者的疗效[J].世界中医药,2018,(12):. |
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| 益气健脾和胃法治疗脾胃虚弱型慢性萎缩性胃炎患者的疗效 |
| Replenishing Qi and Invigorating Spleen and Stomach Therapy in the Treatment of Chronic Atrophic Gastritis with Spleen and Stomach Deficiency Syndrome |
| 投稿时间：2018-04-10 |
| DOI：10.3969/j.issn.1673-7202.2018.12.013 |
| 中文关键词: 益气健脾和胃法 脾胃虚弱证 慢性萎缩性胃炎 中药方剂 胃 肠道 中医证候积分 总有效率 临床疗效 |
| English Keywords:Replenishing qi and invigorating spleen and stomach therapy Spleen and stomach deficiency syndrome Chronicatrophic gastritis Chinese medicine prescriptions stomach intestine traditional Chinese medicine syndrome score total effective rate clinical efficacy |
| 基金项目:攀枝花市重点科研项目（2014c093） |
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| 中文摘要: |
| 目的:探讨益气健脾和胃法对脾胃虚弱型慢性萎缩性胃炎患者的影响。方法:选取2016年1月至2018年1月攀枝花市中心医院消化内科收治的脾胃虚弱型慢性萎缩性胃炎患者100例，按照随机数字表法随机分为观察组和对照组，每组50例，观察组采用健脾和胃汤治疗，对照组采用单纯西药治疗，比较2组治疗前后中医证候积分、临床疗效、胃镜及腺体萎缩、慢性炎性反应、肠腺上皮化生、非典型异形增生检查结果。结果：治疗后，观察组中医证候积分高于对照组，差异有统计学意义(P<0.05)，观察组临床疗效总有效率为90.0％，高于对照组总有效率的72.0％，差异有统计学意义(P<0.05)。观察组胃镜总有效率88％高于对照组68%，差异有统计学意义(P<0.05)。治疗前2组腺体萎缩、慢性炎性反应、肠腺上皮化生、非典型异形增生比较，差异无统计学意义（P>0.05），治疗后2组比较，差异有统计学意义(P<0.05)。结论：益气健脾和胃法对脾胃虚弱型慢性萎缩性胃炎患者疗效显著，有效改善患者临床症状，减少胃腺体萎缩程度、有效控制炎性反应范围。 |
| English Summary: |
| To investigate the effects of replenishing qi and invigorating spleen and stomach therapy on chronicatrophic gastritis with spleen and stomach deficiency syndrome.Methods:A total of 100 chronicatrophic gastritis patients with spleen and stomach deficiency syndrome treated in the department of gastroenterology in Panzhihua Central Hospital from January 2016 to January 2018 were selected and divided into observation group and control group，each with 50 cases.The observation group received the invigorating spleen and stomach therapy，while the control group received the western medicine.The traditional Chinese medicine (TCM) syndrome scores，clinical efficacy，gastroscopy and glandular atrophy，chronic inflammation，intestinal gland metaplasia，and atypical dysplasia were compared before and after treatment in both groups.Results:After treatment，the TCM syndrome scores in the observation group were higher than those in the control group (P<0.05).The total clinical efficacy in the observation group was 90.0%，which was higher than 72.0% of the control group (P<0.05).The total efficiency of gastroscopy in the observation group was 88%，which was higher than 68% of the control group (P<0.05).The glandular atrophy，chronic inflammation，intestinal gland metaplasia，and atypical dysplasia showed no significant difference before treatment (P>0.05)，and there was statistic significance between the groups after the treatment (P<0.05).Conclusion:The clinical efficacy of replenishing qi and invigorating spleen and stomach therapy on chronicatrophic gastritis with spleen and stomach deficiency syndrome is significant，which can ameliorate the clinical symptoms，reduce the gastric gland atrophy degree，effectively control the inflammation extent，which is worthy of practice. |
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