To observe and analyze the effects of Chinese medicine modified "Sini Decoction" on blood glucose, blood lipid and serum glucose transport protein 4 in elderly patients with type 2 diabetes mellitus.Methods:A total of 88 elderly patients with type 2 diabetes and abnormal lipid metabolism treated in the Department of endocrinology in our hospital from January 2016 to December 2016 were randomly divided into control group and treatment group, with 44 cases in each group.The control group was treated with metformin, repaglinide and Atorvastatin, and the observation group was treated with modified Sini Decoction on the basis of treatment group according to TCM syndrome differentiation.The clinical efficacy of the two groups were observed, and the blood lipid before and after treatment (TG), low density lipoprotein cholesterol (LDL-C), fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c), serum glucose transporter 4 (GLUT4) levels were detected and analyzed.Results:After treatment, the levels of FPH, HbA1c, TG and LDL-C in the two groups were significantly decreased (P<0.05), and the treatment group was better than that of the control group (P<0.05).After treatment, GLUT4 levels were significantly increased, and significantly better than the control group (P<0.05).After treatment, the total effective rate of treatment group was 95.45%, and 79.55% in the control group.The treatment group was significantly better than the control group (P<0.05).Conclusion:In the treatment of elderly type 2 diabetic patients with abnormal lipid metabolism in patients, TCM syndrome differentiation combined with Sini Decoction, can more effectively promote the level of GLUT4 in patients with increased glucose metabolism and lipid metabolism level of control, which is worthy of reference and application.