| To observe effects of Jiawei Guizhi Fuling Decoction on serum Anti Miillerian Hormone of polycystic ovary syndrome and endometrial receptivity.Methods:A total of 60 cases of polycystic ovary syndrome(PCOS)with infertility in our hospital from January 2014 to June 2016 were randomly divided into observation group and control group,with 30 cases in each group.The control group was administrated with Clomifene Citrate Capsules,while the observation group was additionally administrated with Jiawei Guizhi Fuling Decoction,with 5 days for a course of treatment.The total course of treatment last for 3 menstrual cycles.The general conditions including the rate of menstruation,the rate of ovulation,the rate of pregnancy,and the rate of abortion were recorded.Transvaginal color Doppler Flow Image(TV-CDFI)was used to measure endometrial thickness and uterine artery blood flow spectrum on the day of ovulation measurement,and the resistance index(RI)and pulsatility index(PI)were calculated.Morning blood were collected to test the sex hormone index of 2 groups before and after the treatment,including serum testosterone(T)and luteinizing hormone(LH),follicle stimulating hormone(FSH)and LH/FSH ratio and serum anti Mullerian hormone(AMH).Results:The levels of T,LH,FSH and LH/FSH in 2 groups decreased to varying degrees,and the trend of the observation group decreased more significantly than that of control group after treatment(P<0.05).Two groups of patients had a certain degree of recovery after treatment.The ovulation rate and pregnancy rate increased,and abortion rate decreased.Statistical analysis showed that the above indicators in the observation group were significantly better than that of control group,and the difference was statistically significant(P<0.05).The endometrium in 2 groups increased,and the levels of RI and PI were reduced to some extent after treatment.The differences between the 2 groups were statistically significant(P<0.05),and the rate of reduction in the observation group was significantly higher than that of control group(P<0.05).The expression levels of AMH in 2 groups increased to varying degrees.Compared with those before treatment,the difference was statistically significant after treatment(P<0.05),and the above indexes in observation group were significantly higher than that of the control group(P<0.05).Conclusion:Jiawei Guizhi Fuling Decoction can significantly improve PCOS in patients with uterine receptivity,improve the ovulation rate and pregnancy rate,and its mechanism may be through decreasing the concentration of AMH,enhance the sensitivity of FSH and promote follicular ovulation related. |
