| 引用本文:赵丹丹1，姜爱荣2，李龙芬1.飞扬穴对腰椎间盘突出镇痛效应的影响及作用机制[J].世界中医药,2018,(12):. |
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| 飞扬穴对腰椎间盘突出镇痛效应的影响及作用机制 |
| Analgesic Effects and Mechanism Research of Feiyang(BL 58)Acupoint on Lumbar Disc Herniation |
| 投稿时间：2018-02-28 |
| DOI：10.3969/j.issn.1673-7202.2018.12.048 |
| 中文关键词: 椎间盘突出症 腰椎 飞扬穴 镇痛 疗效 表面肌电信号 前列腺素E2 β-内啡肽 |
| English Keywords:Lumbar disc herniation Lumber vertebra Feiyang(BL 58)acupoint Analgesic effects Curative effects Surface electromyogram signal Prostaglandin E2 β-endorphin |
| 基金项目:中央级公益性科研院所基本科研业务费中国中医科学院基础所自主选题项目(YZ-1607) |
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| 中文摘要: |
| 目的：评估飞扬穴对腰椎间盘突出症的镇痛效应，同时观察其作用机制。方法：选取2012年1月至2016年12月鄂州市中心医院收治的腰椎间盘突出症患者100例纳入研究，按数字随机数字表法分为对照组及观察组，每组50例。2组患者均接受常规针灸联合脊柱推拿手法，观察组在上述治疗基础上加针刺飞扬穴，1次/d，30 min/次，2组均连续治疗10 d，比较治疗前后患者简易McGill疼痛评分、JOA评分、腰椎活动度、生命质量、腰肌表面肌电信号变化以及治疗前后前列腺素E2(PG E2)、β-内啡肽(β-EP)的水平变化。结果:2组患者治疗后简易McGill疼痛评分、JOA评分均有所改善，其中观察组改善较对照组明显，差异有统计学意义（P<0.05）。2组患者治疗后腰椎前屈活动度及生命质量均较治疗前提高，观察组优于对照组（P<0.05）。治疗后观察组竖脊肌及多裂肌的AEMG、MF、MPF均较对照组改善（P<0.05）。治疗后2组患者外周血PG E2水平有所降低，β-EP水平上调，其中观察组改善得趋势更明显，与对照组比较差异有统计学意义（P<0.05）。结论：飞扬穴可明显改善腰椎间盘突出症患者的疼痛阈值，其可能通过降低外周血PGE2、提高β-EP水平有关。 |
| English Summary: |
| To evaluate analgesic effects and mechanism research of Feiyang(BL 58)acupoint on lumber disc herniation.Methods:One hundred cases of lumbar disc herniation treated in our hospital from January 2012 to December 2016,were included and randomly divided into control group and observation group by random number table method,with 50 cases in each group.Both groups were given routine acupuncture combined spinal massage,and additionally observation group was given needling of Feiyang(BL 58)acupoint,1 time,30 min/time,continuous treatment of 10 d.The changes of simple McGill pain score,JOA score,lumbar flexion mobility,quality of life,surface electric in lumber muscle and prostaglandin E2(PGE2),β-endorphin(β-EP)concentration were compared before and after treatment in 2 groups.Results:1)Simple McGill pain score and JOA scores were improved in both groups.The observation group was better than control group obviously and the difference was statistically significant(P<0.05).2)Front pike position of lumbar flexion mobility and quality of life was improved in both groups.The observation group was better than control group(P<0.05).3)AEMG,MF,and MPF of erector muscle of spine and multifidus of observation group were better than control group(P<0.05).4)PGE2 of peripheral blood levels had fallen in both groups after treatment.β-EP concentration increased.The observation group was better than control group in the improvement trend.It had statistically significant difference(P<0.05).Conclusion:Acupuncture on Feiyang(BL 58)acupoint can significantly improve the pain threshold of lumbar disc herniation,which may be related with reducing peripheral blood PGE2,and improving the concentration ofβ-EP. |
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