世界中医药

作者	单位
余雪1,2,3，李敏谦1,2，郭姣1,2	1 广东省代谢病中西医结合研究中心，广州，510006； 2 广东省代谢性疾病中医药防治重点实验室，广州，510006； 3 广州中医药大学临床药理研究所，广州，510006

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中文摘要:

目的：探讨内脏脂肪指数（Visceral Ddipose Index，VAI）与糖脂代谢病的相关性，计算VAI对糖脂代谢病的诊断切点。方法：纳入1 810例样本，测量体重、身高、腰围，计算BMI、腰高比并进行分组。采用SPSS 19.0进行统计分析。正态分布计量资料以（xX-±s）表示，计数资料以百分数（%）表示，正态分布数据采用单因素方差分析，非正态分布数据采用非参数秩和检验及Spearman秩相关、趋势卡方检验分析，以P<0.05为有统计学意义。结果:VAI与糖脂代谢病有显著相关性。VAI对男性、女性糖脂代谢病患者诊断切点分别是2.0及1.96；VAI对青年、中年、老年糖脂代谢病患者的诊断切点分别是2.06、2.0、1.96。结论：VAI与糖脂代谢病的相关性优于其他人体测量学指标，说明VAI对复杂的综合性病变的预测价值更优，可作为糖脂代谢病早期诊断和疗效评价指标。

English Summary:

To investigate the correlation of Visceral adipose index (VAI) and glycolipid metabolic disease (GLMD)，and calculate a clinical point of tangency VAI to GLMD，which provide reference for the early prevention and treatment of clinical glycolipid metabolic disease. Methods:A total of 1810 samples were included. Ways were used to measured weight，height，waist circumference (WC)，to calculate Body Mass Index (BMI)，waist-high ratio (WHtR)，and to separate them into different groups. The SPSS 19.0 (Statistic Package for Social Science) analyzes statistics was adopted. Measurement data of normal distribution was indicated by (xX-±s) and % (percentage). Normally distributed data use one-way analysis of variance. Non-normally distributed data use non-parametric rank and sum test，spearman rank correlation and trend chi-square test for analyzing. When the data is P<0.05，it means that statistical significance exists. Results:VAI is correlated with GLMD. The VAI clinical point of tangency of GLMD in male is 2.0. The females' clinical point of tangency of is 1.96. The young patients' clinical point of tangency of is 2.06 The middle-aged is 2.0 and the old is 1.96. Conclusion:The correlation between VAI and GLMD is superior to BMI，WC and WHtR. It shows that VAI have predictive value for complex and comprehensive disease as indicators of GLMD's early diagnosis for the prognosis of the disease.

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