| 引用本文:李虎羽1，赵喜燕1，杨俊苹2.复方紫草油治疗小儿湿疹的临床疗效[J].世界中医药,2019,(01):. |
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| 复方紫草油治疗小儿湿疹的临床疗效 |
| Clinical Effects of Compound Radix Arnebiae Oil on Children with Eczema |
| 投稿时间：2018-12-14 |
| DOI：10.3969/j.issn.1673-7202.2019.01.024 |
| 中文关键词: 复方紫草油 小儿湿疹 免疫情况 抗炎效果 |
| English Keywords:Compound Radix Arnebiae Oi Infantile eczema Immunity Anti-inflammatory effects |
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| 中文摘要: |
| 目的：探讨复方紫草油治疗小儿湿疹的临床疗效。方法：选取2015年1月至2017年12月黄河中心医院收治的小儿湿疹患者80例，按照随机数字表法分为对照组和观察组，每组40例，对照组应用肤轻松软膏治疗，观察组应用复方紫草油治疗。分析2组患儿的治疗效果、临床症状缓解情况以及机体免疫改善情况。结果：观察组治疗有效率为95.0%，对照组治疗有效率为80.0%。观察组治疗效果优于对照组（P<0.05）；观察组白细胞介素-4（IL-4）水平明显低于对照组,差异有统计学意义（P<0.05），观察组干扰素-γ（IFN-γ）水平明显高于对照组,差异有统计学意义（P<0.05）；观察组CD8+水平明显低于对照组,差异有统计学意义（P<0.05），观察组CD4+、CD4+/CD8+水平明显高于对照组,差异有统计学意义（P<0.05）；观察组证候积分改善优于对照组,差异有统计学意义（P<0.05），观察组住院时间明显少于对照组,差异有统计学意义（P<0.05）；2组均未出现严重不良反应，轻微不良反应在调整用药后缓解，2组不良反应比较，差异无统计学意义（P>0.05）。结论：复方紫草油治疗小儿湿疹效果理想。 |
| English Summary: |
| To explore the clinical efficacy of Compound Radix Arnebiae Oil in the treatment of childhood eczema. Methods:A total of 80 pediatric eczema patients admitted to Yellow River Central Hospital from January 2015 to December 2017 were selected and divided into 2 groups according to the random number table，with 40 cases in each group. The control group was treated with skin lightening ointment and the research group was treated with Compound Radix Arnebiae Oil. The therapeutic effects，clinical symptoms and immune improvement of the 2 groups were analyzed. Results:The effective rate was 95.0% in the study group and 80.0% in the control group. The treatment effect of the study group was significantly better than that of the control group (P<0.05). The level of il-4 in the study group was significantly lower than that in the control group (P<0.05)，and the level of ifn-alpha in the study group was significantly higher than that in the control group (P<0.05). The CD8+ level of the study group was significantly lower than that of the control group (P<0.05)，and the CD4+ and CD4+/CD8+ levels of the study group were significantly higher than those of the control group (P<0.05). The improvement of symptom score of the study group was better than that of the control group (P<0.05)，and the hospitalization time of the study group was significantly less than that of the control group (P<0.05). Severe adverse reactions were found in both groups，and minor adverse reactions were relieved after adjustment of medication. There was no statistically significant difference in the occurrence of adverse reactions between the 2 groups (P<0.05). Conclusion:Compound Radix Arnebiae Oil is effective in treating infantile eczema and should be widely used in clinic. |
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