世界中医药
文章摘要
引用本文:李敏谦1,3,林育2,项磊2,3,朴胜华1,2,朱青1,2,郭姣1,2.瘅浊与糖脂代谢病[J].世界中医药,2019,(03):.  
瘅浊与糖脂代谢病
Dan-Zhuo and Glucolipid Metabolic Disorders
投稿时间:2019-02-01  
DOI:10.3969/j.issn.1673-7202.2019.03.025
中文关键词:  “瘅浊”  糖脂代谢病  中医病名  糖脂代谢紊乱
English Keywords:Dan-Zhuo  Glucolipid Metabolic Disorders  TCM disease name  Glucolipid metabolism disorder
基金项目:国家自然科学基金重点项目(81530102);粤港联合糖脂代谢病诊断生物标志物研发创新平台(2017B050504005)
作者单位
李敏谦1,3,林育2,项磊2,3,朴胜华1,2,朱青1,2,郭姣1,2 1 广东药科大学中医药研究院广州510006
2 广东省代谢病中西医结合研究中心广州510006
3 广东药科大学附属第一医院广州510080 
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中文摘要:
      糖脂代谢病(GLMD)是表现为高血糖、血脂异常、非酒精性脂肪性肝病、超重、高血压、动脉粥样硬化性心脑血管病等一种或多种形式的疾病,其发病机制复杂,目前尚无特定的中医病名。本文基于中医疾病命名常用方法,从GLMD的临床症状、病情、病因、病位、病机、病性6个方面对其中医命名进行逐一解析。最终,根据文献资料与临床实践情况,从病机与病性相结合角度,将GLMD命名为“瘅浊”,既能涵盖疾病内涵,又能同时反映疾病病机、病性等特点。“瘅”主要指“热”“湿热”“劳病”,瘅之为患可损伤全身多个脏腑,包括脾瘅、胃瘅、肾瘅、胆瘅、心瘅、消瘅、肝(胆)瘅等;“浊”指湿、痰、瘀、毒等病理之浊,现代医学糖、脂代谢紊乱的病理变化及其产物如高血糖、高脂血症、非酒精性脂肪肝、超重、高血压、动脉粥样硬化等均可归属于“瘅浊”的范畴。“瘅浊”规范了GLMD中医病名及疾病范畴,丰富和发展了中医学疾病理论体系,为整体认识和一体化防控糖脂代谢性疾病提供了中医理论基础。
English Summary:
      Glucolipid Metabolic Disorders(GLMD)is one disease which clinical feature manifest itself as one or more of these kinds of diseases such as hyperglycemia,dyslipidemia,non-alcoholic fatty liver disease(NAFLD),overweight,hypertension,atherosclerotic cardio-cerebrovascular disease,with complex pathogenesis.The traditional Chinese medicine(TCM)name of GLMD has not been defined.Based on the common methods denominating a disease of TCM,this paper analyzes the GLMD denomiation of Chinese medicines from six aspects:symptoms,conditions,etiology,location of the disease,pathogenesis and the nature of disease.On the grounds of literatures and clinical practice,and from the perspective of the combination of the pathogenesis and the nature of disease,the denomination of GLMD as Dan-Zhuo enables to not only cover its connotation but also reveals its characteristics.“Dan” refers to “Heat”,“Dampness-heat”,“Consumptive disease”,include “Spleen-Dan”,“Stomach-Dan”,“Kidney-Dan”,“Gallbladder-Dan”,“Heart-Dan” and “Wasting-Dan”.“Zhuo” refers to dampness,phlegm,stasisand toxin and so on.Diseases like hyperglycemia,hyperlipidemia,NAFLD,overweight,hypertension,atherosclerotic cardio-cerebrovascular disease and so on can be attributed to the pathological "Dan-Zhuo" of traditional Chinese medicine.The denomination of “Dan-Zhuo” regulates category of the naming and disease of TCM in GLMD,also enriches and develops the theoretical system of TCM diseases,providing a theoretical basis for TCM understanding and integration of prevention and treatment of GLMD.
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