| 引用本文:王飞1，饶峰1，秦亚勤1，赵福兰2.川蛭通络胶囊联合瑞舒伐他汀对血脂正常急性脑梗死患者的疗效[J].世界中医药,2019,(04):. |
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| 川蛭通络胶囊联合瑞舒伐他汀对血脂正常急性脑梗死患者的疗效 |
| Effects of Chuanzhi Tongluo Capsule Combined with Rosuvastatin on Patients with Acute Cerebral Infarction with Normal Blood Lipid |
| 投稿时间：2019-03-12 |
| DOI：10.3969/j.issn.1673-7202.2019.04.019 |
| 中文关键词: 川蛭通络胶囊 瑞舒伐他汀 急性脑梗死 血脂 神经功能损伤 疗效 评分 |
| English Keywords:Chuanzhi Tongluo capsule Rosuvastatin Acute cerebral infarction Blood lipid Neurological deficit Curative effects Scores |
| 基金项目:国家中医药重点专科建设项目（ZY044651） |
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| 中文摘要: |
| 目的：探讨川蛭通络胶囊联合瑞舒伐他汀对血脂正常急性脑梗死患者的疗效。方法：选取2017年12月至2018年12月阜阳市人民医院收治的急性脑梗死患者（血脂正常）80例作为研究对象，随机分为观察组和对照组，每组40例。观察组使用川蛭通络胶囊（0.5 g，3次/d）联合瑞舒伐他汀（10 mg，1次/d）治疗，对照组使用同等剂量瑞舒伐他汀治疗。根据神经功能缺损评分制定疗效标准，统计神经功能损伤评分和有效率，观察治疗前后超敏C反应蛋白水平，比较2组患者的治疗效果。结果：2组患者治疗后神经功能缺损评分均显著低于治疗前，组间比较差异有统计学意义（P<0.05）；观察组治疗后的超敏C反应蛋白水平显著低于对照组（P<0.05）；观察组治疗总有效率97.5%，对照组治疗总有效率82.5%，2组比较差异有统计学意义(P<0.05)。2组患者用药期间均无明显不良反应。结论：川蛭通络胶囊联合瑞舒伐他汀治疗血脂正常急性脑梗死的疗效显著优于瑞舒伐他汀单药治疗，且显著降低超敏C反应蛋白水平，值得临床应用。 |
| English Summary: |
| To explore the curative effects of Chuanzhi Tongluo capsule combined with rosuvastatin on patients with acute cerebral infarction with normal blood lipid.Methods:A total of 80 patients with acute cerebral infarction(normal blood lipid）in Fuyang People's Hospital from December 2017 to December 2018 were randomly divided into 2 groups，with 40 cases in each group.The observation group was treated with Chuanzhi Tongluo capsule and rosuvastatin，while the control group was treated with rosuvastatin.According to the neurologic impairment score，the curative effect standard was established，and the therapeutic effects of the 2 groups were compared.The hypersensitivity C-protein level before and after treatment was compared.T-test and Chi-square test were used to measure the treatment effect between the 2 groups.Results:The neurological deficit scores of the 2 groups after treatment were significantly lower than those before treatment(P<0.05).The differences between the 2 groups after treatment were statistically significant(P<0.05).The level of high-sensitivity C-reactive protein in the observation group after treatment was significantly lower than that in the control group(P<0.05).The total effective rate was 97.5% in the observation group and 82.5% in the control group.The difference between the 2 groups was statistically significant(P<0.05).There were no obvious adverse reactions in the 2 groups.Conclusion:The curative effects of Chuanzhi Tongluo capsule combined with rosuvastatin on acute cerebral infarction with normal blood lipid is better than that of rosuvastatin，which is clinically worthy of application. |
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