世界中医药
文章摘要
引用本文:胡虹宇1,孔祥东2,王叔1.平肝解郁汤对产妇产后抑郁症的改善及对性激素水平的影响[J].世界中医药,2019,(04):.  
平肝解郁汤对产妇产后抑郁症的改善及对性激素水平的影响
Improvement of Pinggan Jieyu Decoction on Postpartum Depression and Its Effects on Levels of Sex Hormone
投稿时间:2019-01-10  
DOI:10.3969/j.issn.1673-7202.2019.04.025
中文关键词:  平肝解郁汤  产后抑郁症  疗效  性激素  心理疏导  焦虑
English Keywords:Pinggan Jieyu decoction  Postpartum depression  Efficacy  Sex hormone  psychological counseling  Anxiety
基金项目:国家科学技术部重点研发计划项目(2018YFC1002203)——基于生物学技术的遗传病产前筛查与诊断规范化体系研究
作者单位
胡虹宇1,孔祥东2,王叔1 1 河南省濮阳市第三人民医院产科,濮阳,457000
2 郑州大学第一附属医院遗传与产前诊断中心,郑州,450052 
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中文摘要:
      目的:探讨平肝解郁汤对产妇产后抑郁症(PPD)的改善及对性激素水平的影响。方法:选取2016年10月至2018年8月濮阳市第三人民医院收治的PPD患者102例作为研究对象,按照随机数字表法随机分为观察组和对照组,每组51例。2组患者均给予心理疏导,观察组在此基础上增加平肝解郁汤治疗,2组均连续治疗3个月。比较2组患者治疗后临床疗效、治疗前后EPDS、HAMD评分、中医临床症状改善情况及性激素水平。结果:治疗后观察组总有效率明显高于对照组(P<0.05)。与治疗前比较,治疗后2组患者EPDS、HAMD及心情抑郁等各项中医临床症状评分均明显降低,且观察组明显低于对照组(P<0.01)。与治疗前比较,治疗后2组患者血清E2水平明显升高,且观察组明显高于对照组(P<0.01);2组P水平明显降低,且观察组明显低于对照组(P<0.01)。结论:在心理疏导的基础上给予平肝解郁汤治疗可更明显地调节PPD患者性激素水平,改善患者焦虑情绪及各项中医临床症状,提高整体治疗效果,建议临床推广使用。
English Summary:
      To explore the improvement of Pinggan Jieyu Decoction on postpartum depression (PPD) and its influence on levels of sex hormone.Methods:A total of 102 patients with PPD who were treated in Puyang Third People's Hospital from October 2016 to August 2018 were selected and divided into the observation group and the control group using random number table method,with 51 cases in each group.The patients in the 2 groups were given psychological counseling.The observation group added Pinggan Jieyu Decoction on this basis.The 2 groups were treated continuously for 3 months.The clinical efficacy after treatment,the scores of EPDS,HAMD,the improvement of clinical symptoms of TCM and the levels of sex hormones were compared before and after treatment between the 2 groups.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group (P<0.05).Compared with before treatment,the scores of EPDS,HAMD and clinical symptoms of TCM such as mood depression significantly decreased,and the observation group was significantly lower than the control group (P<0.01).Compared with before treatment,the levels of serum E2 significantly increased in the 2 groups after treatment,and the observation group was significantly higher than the control group (P<0.01); the levels of P significantly decreased,and the observation group was significantly lower than the control group (P<0.01).Conclusion:Using Pinggan Jieyu decoction on the basis of psychological counseling can significantly regulate the levels of sex hormone in patients with PPD,improve the anxiety and various clinical symptoms of TCM of patients,and enhance the overall treatment effect,which is recommend to use in clinic.
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