To investigate the effects of multi-phase administration of Bushen Tiaojing Decoction on ovulation outcomes, symptoms and sex hormone levels in patients with polycystic ovary syndrome (PCOS). Methods:A total of 80 patients with PCOS treated in Qingdao Central Hospital from January 2014 to January 2016 were selected and randomly divided into observation group and control group, with 40 cases in each group. Patients in control group received conventional western medicine treatment of clomiphene citrate tablets and ethinylestradiol cyproterone tablets, and the observation group additionally received the Bushen Tiaojing Decoction on the basis of the same western medicine treatment, both were treated for 3 months. The levels of sex hormones, insulin resistance index (HOMA-IR), serum leptin (LP) level and traditional Chinese medicine (TCM) syndrome score in two groups before and after treatment were compared. The menstrual recovery, ovulation and pregnancy in two groups were compared during the 24 months follow-up. Results:The total effective rate of treatment in the observation group was 82.50%, which was significantly higher than that of the control group (65%), and the difference was statistically significant (P<0.05). After treatment, the TCM symptom scores were significantly reduced, and the observation group was significantly lower than the control group, the difference was statistically significant (P<0.05). There was a statistically significant difference in luteinizing hormone (LH), estradiol (E2), serum testosterone (T) and follicle stimulating hormone (FSH) between the two groups before and after treatment (P<0.05), and the difference after treatment between two groups was statistically significant (P<0.05). After treatment, the levels of HOMA-IR and serum LP in the two groups were significantly decreased, and the observation group was significantly lower than the control group, and the difference was statistically significant (P<0.05). The number of menstrual recovery, ovulation and pregnancy in the observation group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion:Bushen Tiaojing Decoction combined with western medicine can significantly ameliorate the level of sex hormones and clinical symptoms, as well as promote ovulation, menstrual recovery and pregnancy in PCOS patients.