| 引用本文:胡静，张冰冰，金珠，陈，杰，陈晛，路建饶，何立群.益肾活血泄浊方联合陆氏针灸治疗糖尿病肾病Ⅲ期临床疗效观察〖JZ)〗〖HS)〗[J].世界中医药,2019,(05):. |
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| 益肾活血泄浊方联合陆氏针灸治疗糖尿病肾病Ⅲ期临床疗效观察〖JZ)〗〖HS)〗 |
| Clinical Efficacy Observation of Yishen Huoxue Xiezhuo Decoction Combined with Lu's Acupuncture and Moxibustion in Treating Phase III Diabetic Nephropathy |
| 投稿时间：2019-04-10 |
| DOI：10.3969/j.issn.1673-7202.2019.05.010 |
| 中文关键词: 糖尿病肾病 CKD1-3 陆氏针灸 临床疗效 血清C反应蛋白 血尿酸 尿微量蛋白 血肌酐 |
| English Keywords:Diabetic nephropathy CKD1-3 Lu's acupuncture and moxibustion Clinical efficacy Serum C-reactive protein Uric acid BUA Urine microprotein Serum creatinine Scr |
| 基金项目:上海市浦东新区科技和经济委员会科技发展基金民生科研专项资金项目(PKJ2017-Y15) |
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| 中文摘要: |
| 目的:研究观察糖尿病肾病Ⅲ期患者在经过益肾活血泄浊方单独和联合陆氏针灸治疗前后患者临床的疗效。方法:采用前瞻性随机对照临床研究的方法,选取2017年1月至2018年12月上海中医药大学附属第七人民医院收治的肾病糖尿病患者90例作为研究对象,按照随机对照的原则分为A组：A组给予西药常规治疗,B组:B组在西药治疗基础上加益气活血泄浊方口服,C组:C组在中西药治疗的基础上加上针灸治疗。3组都以2个月为1个疗程,共治疗3个疗程,观察3组患者治疗前及治疗后2、4、6个月尿微量白蛋白、肾功能(血肌酐、肾小球滤过率、血尿酸),C-反应蛋白、纤维蛋白原、胰岛素抵抗指数)以及炎性细胞因子,评价临床疗效,为中西药联合陆氏针灸内外合治早期糖尿病肾病提供科学依据。结果:经过比较治疗前后的各项指标,A、B、C 3组患者治疗后症状均得到了一定的缓解,临床效果比较C组好于B组,B组好于A组,C组患者各项生理指标均改善最明显,效果最显著。结论:中西医联合针灸综合疗法对于治疗早期的糖尿病肾病临床效果更加显著。 |
| English Summary: |
| To observe the clinical efficacy of patients with phase III diabetic nephropathy before and after treatment with Yishen Huoxue Xiezhuo decoction alone and combined with Lu's acupuncture and moxibustion.Methods:Using a prospective randomized controlled clinical study approach,90 patients of diabetic nephropathy admitted to the Seventh People's Hospital of Chinese medicine from January 2017 to December 2018 were selected as subjects.According to the principle of randomized control,they were divided into group A:western medicine control group was given conventional western medicine,group B:Chinese and western medicine treatment group was given Yishen Huoxue Xiezhuo decoction on the basis of western medicine treatment,group C:Chinese and western medicine combined with Lu's acupuncture and moxibustion treatment group on the basis of Chinese and western medicine.All of the 3 groups were treated with 2 months as a course of treatment,and a total of 3 courses were treated.The urinary microalbumin,renal function(serum creatinine,glomerular filtration rate,blood uric acid)C-reactive protein,fibrinogen,insulin resistance index and inflammatory cytokines were observed before treatment and after 2,4 and 6 months after treatment,evaluating the efficacy and providing a scientific basis for the treatment of early diabetic nephropathy by Chinese and western medicine combined with Lu's acupuncture.Results:After comparing the indicators before and after treatment,the symptoms of patients in group A,B,and C were all relieved after treatment.The clinical effect in the group C was better than those in the group B,and the clinical effect in the group B was better than those in the group A,the physiological indexes of patients in group C were the most obvious,and the effect was the most significant.Conclusion:Chinese and western medicine combined acupuncture and moxibustion therapy is more effective in treating early diabetic nephropathy. |
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